Targeting plasma membrane GRP78 for cancer growth inhibition
- PMID: 20026905
- DOI: 10.4161/cbt.9.2.10760
Targeting plasma membrane GRP78 for cancer growth inhibition
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Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.Cancer Biol Ther. 2010 Jan;9(2):142-52. doi: 10.4161/cbt.9.2.10422. Epub 2010 Jan 26. Cancer Biol Ther. 2010. PMID: 20368692
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