Persistence in darkness of virulent alphaviruses, Ebola virus, and Lassa virus deposited on solid surfaces
- PMID: 20842393
- DOI: 10.1007/s00705-010-0791-0
Persistence in darkness of virulent alphaviruses, Ebola virus, and Lassa virus deposited on solid surfaces
Abstract
Ebola, Lassa, Venezuelan equine encephalitis, and Sindbis viruses were dried onto solid surfaces, incubated for various time periods under controlled conditions of temperature and relative humidity, and quantitatively eluted from surfaces, and viral titers in the recovered samples were determined. The viral inactivation kinetics that were obtained indicated that viral resistance to natural inactivation in the dark follows (in decreasing order of stability) alphavirus > Lassa virus > Ebola virus. The findings reported in this study on the natural decay in the dark should assist in understanding the biophysical properties of enveloped RNA viruses outside the host and in estimating the persistence of viruses in the environment during epidemics or after an accidental or intentional release.
Similar articles
-
Sensitivity to ultraviolet radiation of Lassa, vaccinia, and Ebola viruses dried on surfaces.Arch Virol. 2011 Mar;156(3):489-94. doi: 10.1007/s00705-010-0847-1. Epub 2010 Nov 23. Arch Virol. 2011. PMID: 21104283
-
Persistence of Bacteriophage Phi 6 on Porous and Nonporous Surfaces and the Potential for Its Use as an Ebola Virus or Coronavirus Surrogate.Appl Environ Microbiol. 2020 Aug 18;86(17):e01482-20. doi: 10.1128/AEM.01482-20. Print 2020 Aug 18. Appl Environ Microbiol. 2020. PMID: 32591388 Free PMC article.
-
Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin.Arch Virol. 2012 Jan;157(1):121-7. doi: 10.1007/s00705-011-1115-8. Epub 2011 Sep 25. Arch Virol. 2012. PMID: 21947546
-
[Viral hemorrhagic fever--Ebola hemorrhagic fever, Marburg disease and Lassa fever].Rinsho Byori. 1998 Jul;46(7):651-5. Rinsho Byori. 1998. PMID: 9721531 Review. Japanese.
-
The regulation of disassembly of alphavirus cores.Arch Virol. 2009;154(3):381-90. doi: 10.1007/s00705-009-0333-9. Epub 2009 Feb 19. Arch Virol. 2009. PMID: 19225713 Review.
Cited by
-
In Silico Screening of Inhibitors of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease.Viruses. 2023 Jul 4;15(7):1503. doi: 10.3390/v15071503. Viruses. 2023. PMID: 37515189 Free PMC article.
-
Decontamination efficacy of common liquid disinfectants against non-spore-forming biological agents in soil matrices.J Appl Microbiol. 2022 Dec;133(6):3659-3668. doi: 10.1111/jam.15802. Epub 2022 Sep 13. J Appl Microbiol. 2022. PMID: 36056613 Free PMC article.
-
903 Protein Saver cards: the best alternative for dried blood spot storage at room temperature for HCV RNA.Sci Rep. 2022 Jun 16;12(1):10124. doi: 10.1038/s41598-022-14375-8. Sci Rep. 2022. PMID: 35710721 Free PMC article.
-
Henipaviruses-A constant threat to livestock and humans.PLoS Negl Trop Dis. 2022 Feb 18;16(2):e0010157. doi: 10.1371/journal.pntd.0010157. eCollection 2022 Feb. PLoS Negl Trop Dis. 2022. PMID: 35180217 Free PMC article. Review.
-
Evaluation of environmental conditions as a decontamination approach for SARS-CoV-2 when applied to common library, archive and museum-related materials.J Appl Microbiol. 2022 Apr;132(4):3405-3415. doi: 10.1111/jam.15468. Epub 2022 Feb 15. J Appl Microbiol. 2022. PMID: 35094472 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
