Green tea and cancer prevention
- PMID: 20924968
- DOI: 10.1080/01635581.2010.509536
Green tea and cancer prevention
Abstract
Extracts of green tea and green tea polyphenols have exhibited inhibitory effects against the formation and development of tumors at different organ sites in animals. These include animal models for skin, lung, oral cavity, esophagus, stomach, intestine, colon, liver, pancreas, bladder, mammary gland, and prostate cancers. In addition to suppressing cell proliferation, promoting apoptosis, and modulating signaling transduction, green tea polyphenols, especially (-)-epigallocatechin-3-gallate, also inhibit cell invasion, angiogenesis, and metastasis. This article reviews data on the cancer preventive activities of green tea polyphenols, possible mechanisms involved, and the relationship between green tea consumption and human cancer risk.
Similar articles
-
Downstream carcinogenesis signaling pathways by green tea polyphenols: a translational perspective of chemoprevention and treatment for cancers.Curr Drug Metab. 2014 Jan;15(1):14-22. doi: 10.2174/1389200214666131211155613. Curr Drug Metab. 2014. PMID: 24329111 Review.
-
Cancer prevention by tea: Evidence from laboratory studies.Pharmacol Res. 2011 Aug;64(2):113-22. doi: 10.1016/j.phrs.2011.03.001. Epub 2011 Mar 21. Pharmacol Res. 2011. PMID: 21397027 Review.
-
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance.Nat Rev Cancer. 2009 Jun;9(6):429-39. doi: 10.1038/nrc2641. Nat Rev Cancer. 2009. PMID: 19472429 Free PMC article. Review.
-
Green tea polyphenols: biology and therapeutic implications in cancer.Front Biosci. 2007 Sep 1;12:4881-99. doi: 10.2741/2435. Front Biosci. 2007. PMID: 17569617 Review.
-
Tea and cancer prevention: molecular mechanisms and human relevance.Toxicol Appl Pharmacol. 2007 Nov 1;224(3):265-73. doi: 10.1016/j.taap.2006.11.024. Epub 2006 Nov 29. Toxicol Appl Pharmacol. 2007. PMID: 17234229 Free PMC article. Review.
Cited by
-
Natural Immunomodulatory Agents as a Complementary Therapy for Poxviruses.Adv Exp Med Biol. 2024;1451:337-354. doi: 10.1007/978-3-031-57165-7_22. Adv Exp Med Biol. 2024. PMID: 38801589 Review.
-
Unveiling the Mechanisms of EGCG-p53 Interactions through Molecular Dynamics Simulations.ACS Omega. 2024 Apr 23;9(18):20066-20085. doi: 10.1021/acsomega.3c10523. eCollection 2024 May 7. ACS Omega. 2024. PMID: 38737068 Free PMC article.
-
Investigating the potential causal association between consumption of green tea and risk of lung cancer: a study utilizing Mendelian randomization.Front Nutr. 2024 Feb 19;11:1265878. doi: 10.3389/fnut.2024.1265878. eCollection 2024. Front Nutr. 2024. PMID: 38439922 Free PMC article.
-
The potential anti-cancer effects of quercetin on blood, prostate and lung cancers: An update.Front Immunol. 2023 Feb 28;14:1077531. doi: 10.3389/fimmu.2023.1077531. eCollection 2023. Front Immunol. 2023. PMID: 36926328 Free PMC article. Review.
-
Tea Polyphenols and Their Preventive Measures against Cancer: Current Trends and Directions.Foods. 2022 Oct 25;11(21):3349. doi: 10.3390/foods11213349. Foods. 2022. PMID: 36359962 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
