Maternal and infant outcomes among severely ill pregnant and postpartum women with 2009 pandemic influenza A (H1N1)--United States, April 2009-August 2010
- PMID: 21900872
Maternal and infant outcomes among severely ill pregnant and postpartum women with 2009 pandemic influenza A (H1N1)--United States, April 2009-August 2010
Abstract
Pregnant women with influenza are at increased risk for hospitalization and death. Since 2004, the Advisory Committee on Immunization Practices (ACIP) has recommended inactivated influenza vaccine for all women who are pregnant during influenza season, regardless of trimester. Nonetheless, after the 2004 recommendation, estimated annual influenza vaccination coverage among pregnant women was approximately 15%, before increasing to nearly 50% during the 2009 influenza A (H1N1) pandemic. Since April 2009, CDC has collaborated with state and local health departments to conduct enhanced surveillance for severe influenza among pregnant and postpartum women. To assess maternal and infant outcomes among severely ill pregnant and postpartum women with 2009 H1N1 during the 2009 H1N1 pandemic, CDC analyzed data for the period April 15, 2009 to August 10, 2010. This report summarizes the results of that analysis, which found that, among 347 severely ill pregnant women, 75 died from 2009 H1N1, and 272 were admitted to an intensive-care unit (ICU) and survived. Women who survived received antiviral treatment sooner after symptom onset than women who died. Pregnant women with severe influenza who delivered during their influenza hospitalization were more likely to deliver preterm and low birth weight infants than those in the general U.S. population; infants born after their mother's influenza hospitalization discharge were more likely to be small for gestational age. These data document the severe effects of 2009 H1N1 on pregnant women and their infants, emphasize the importance of vaccinating pregnant women against influenza, and demonstrate the value of prompt administration of antivirals to pregnant women with suspected or confirmed influenza.
Similar articles
-
Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021-22 Influenza Season.MMWR Recomm Rep. 2021 Aug 27;70(5):1-28. doi: 10.15585/mmwr.rr7005a1. MMWR Recomm Rep. 2021. PMID: 34448800 Free PMC article.
-
Effects of influenza on pregnant women and infants.Am J Obstet Gynecol. 2012 Sep;207(3 Suppl):S3-8. doi: 10.1016/j.ajog.2012.06.068. Epub 2012 Jul 9. Am J Obstet Gynecol. 2012. PMID: 22920056 Review.
-
Review of the pandemic (H1N1) 2009 among pregnant Japanese women.J Obstet Gynaecol Res. 2012 May;38(5):757-62. doi: 10.1111/j.1447-0756.2011.01812.x. Epub 2012 Apr 9. J Obstet Gynaecol Res. 2012. PMID: 22487092 Review.
-
Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States.JAMA. 2010 Apr 21;303(15):1517-25. doi: 10.1001/jama.2010.479. JAMA. 2010. PMID: 20407061 Free PMC article.
-
Severe 2009 H1N1 influenza in pregnant and postpartum women in California.N Engl J Med. 2010 Jan 7;362(1):27-35. doi: 10.1056/NEJMoa0910444. Epub 2009 Dec 23. N Engl J Med. 2010. PMID: 20032319
Cited by
-
A Mother's Dilemma: The 5-P Model for Vaccine Decision-Making in Pregnancy.Vaccines (Basel). 2023 Jul 17;11(7):1248. doi: 10.3390/vaccines11071248. Vaccines (Basel). 2023. PMID: 37515063 Free PMC article.
-
COVID-19 Vaccine Hesitancy among English-Speaking Pregnant Women Living in Rural Western United States.Vaccines (Basel). 2023 Jun 16;11(6):1108. doi: 10.3390/vaccines11061108. Vaccines (Basel). 2023. PMID: 37376496 Free PMC article.
-
The perinatal health challenges of emerging and re-emerging infectious diseases: A narrative review.Front Public Health. 2023 Jan 5;10:1039779. doi: 10.3389/fpubh.2022.1039779. eCollection 2022. Front Public Health. 2023. PMID: 36684933 Free PMC article. Review.
-
Timing and severity of COVID-19 during pregnancy and risk of preterm birth in the International Registry of Coronavirus Exposure in Pregnancy.BMC Pregnancy Childbirth. 2022 Oct 18;22(1):775. doi: 10.1186/s12884-022-05101-3. BMC Pregnancy Childbirth. 2022. PMID: 36258186 Free PMC article.
-
Role of hormones in the pregnancy and sex-specific outcomes to infections with respiratory viruses.Immunol Rev. 2022 Jul;308(1):123-148. doi: 10.1111/imr.13078. Epub 2022 Apr 4. Immunol Rev. 2022. PMID: 35373371 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous