Semen variation in a population of fertile donors: evaluation in a French centre over a 34-year period
- PMID: 22150270
- DOI: 10.1111/j.1365-2605.2011.01229.x
Semen variation in a population of fertile donors: evaluation in a French centre over a 34-year period
Abstract
Although it has been suspected that there is a decrease in semen quality over time, the results reported to date remain debatable because of methodological issues. The aim of the study reported here was to investigate the evolution of semen quality over time in a population of 1114 fertile candidates for sperm donation at CECOS, Tours, between 1976 and 2009. We investigated semen volume, sperm concentration, progressive motility, vitality, percentage of normal forms and multiple abnormalities index of the first ejaculate in this population. We did not find a decline in semen volume, whereas we observed a significant decrease in total sperm count (from 443.2 million in 1976 to 300.2 million in 2009), motility (from 64% in 1976 to 49% in 2009) and vitality (from 88% to 80%). Moreover, a significant decline in the percentage of normal forms was noted between 1976 and 1997 (from 67% to 26%) with a steady rise in the multiple abnormalities index between 1998 and 2009 (from 1.19 to 1.65). This study involving a population of fertile men from a restricted area revealed various degrees of decline in semen parameters over a period of 34 years. These findings will have to be compared with findings in other geographical areas.
© 2011 The Authors. International Journal of Andrology © 2011 European Academy of Andrology.
Similar articles
-
[Reference values of semen parameters for normal fertile men in Shanghai].Zhonghua Nan Ke Xue. 2012 May;18(5):400-3. Zhonghua Nan Ke Xue. 2012. PMID: 22741435 Chinese.
-
Freezability and semen parameters in candidates of sperm bank donors: 1992-2010.J Androl. 2012 Sep-Oct;33(5):999-1006. doi: 10.2164/jandrol.111.013045. Epub 2012 Jan 26. J Androl. 2012. PMID: 22282433
-
World Health Organization reference values for human semen characteristics.Hum Reprod Update. 2010 May-Jun;16(3):231-45. doi: 10.1093/humupd/dmp048. Epub 2009 Nov 24. Hum Reprod Update. 2010. PMID: 19934213 Review.
-
[Analysis of decline in seminal fluid in the Italian population during the past 15 years].Minerva Ginecol. 1999 Jun;51(6):223-31. Minerva Ginecol. 1999. PMID: 10479874 Review. Italian.
-
Decline in semen quality among fertile men in Paris during the past 20 years.N Engl J Med. 1995 Feb 2;332(5):281-5. doi: 10.1056/NEJM199502023320501. N Engl J Med. 1995. PMID: 7816062
Cited by
-
Decline of Sperm Quality over the Last Two Decades in the South of Europe: A Retrospective Study in Infertile Patients.Biology (Basel). 2022 Dec 30;12(1):70. doi: 10.3390/biology12010070. Biology (Basel). 2022. PMID: 36671762 Free PMC article.
-
Impact of Nanoparticles on Male Fertility: What Do We Really Know? A Systematic Review.Int J Mol Sci. 2022 Dec 29;24(1):576. doi: 10.3390/ijms24010576. Int J Mol Sci. 2022. PMID: 36614018 Free PMC article. Review.
-
Spatiotemporal trends in human semen quality.Nat Rev Urol. 2022 Oct;19(10):597-626. doi: 10.1038/s41585-022-00626-w. Epub 2022 Aug 17. Nat Rev Urol. 2022. PMID: 35978007 Free PMC article. Review.
-
Male Reproductive Health - study of a sperm donor population.JBRA Assist Reprod. 2022 Apr 17;26(2):247-254. doi: 10.5935/1518-0557.20210064. JBRA Assist Reprod. 2022. PMID: 35389042 Free PMC article.
-
Systematic Analysis of Breed, Methodological, and Geographical Impact on Equine Sperm Progressive Motility.Animals (Basel). 2021 Oct 29;11(11):3088. doi: 10.3390/ani11113088. Animals (Basel). 2021. PMID: 34827820 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical