The role of procalcitonin in community-acquired pneumonia: a literature review
- PMID: 22842969
- DOI: 10.1097/TME.0b013e318261338d
The role of procalcitonin in community-acquired pneumonia: a literature review
Abstract
Community-acquired pneumonia (CAP) is a significant clinical and public health problem. Recently, attention has been paid to the potential for procalcitonin (PCT) both to differentiate the diagnosis and to indicate the prognosis of pneumonia. The purpose of this literature review was to evaluate the eligibility of PCT for defining typical bacterial infections and for predicting severity and mortality in trials for CAP. The literature review suggests that PCT has the ability to supplement clinical information to determine whether or not the cause of the infection is likely to be bacterial. In addition, PCT seems to be superior to the most prevalent inflammatory biomarker C-reactive protein and also demonstrates a significant correlation between the current clinical scoring systems and actual mortality.
Similar articles
-
Procalcitonin predicts patients at low risk of death from community-acquired pneumonia across all CRB-65 classes.Eur Respir J. 2008 Feb;31(2):349-55. doi: 10.1183/09031936.00054507. Epub 2007 Oct 24. Eur Respir J. 2008. PMID: 17959641
-
Utility of serum procalcitonin and C-reactive protein in severity assessment of community-acquired pneumonia in children.Clin Biochem. 2016 Jan;49(1-2):47-50. doi: 10.1016/j.clinbiochem.2015.09.008. Epub 2015 Sep 18. Clin Biochem. 2016. PMID: 26386341
-
The value of procalcitonin level in community-acquired pneumonia in the ED.Am J Emerg Med. 2012 Sep;30(7):1248-54. doi: 10.1016/j.ajem.2011.08.009. Epub 2011 Oct 24. Am J Emerg Med. 2012. PMID: 22030193
-
Biological markers to determine eligibility in trials for community-acquired pneumonia: a focus on procalcitonin.Clin Infect Dis. 2008 Dec 1;47 Suppl 3:S127-32. doi: 10.1086/591393. Clin Infect Dis. 2008. PMID: 18986278 Review.
-
The role of procalcitonin in adult patients with community-acquired pneumonia--a systematic review.Dan Med J. 2012 Mar;59(3):A4357. Dan Med J. 2012. PMID: 22381083 Review.
Cited by
-
Serum procalcitonin has no significance in the diagnosis of periprosthesis joint infection before total hip and knee replacement.Front Surg. 2023 Nov 6;10:1216103. doi: 10.3389/fsurg.2023.1216103. eCollection 2023. Front Surg. 2023. PMID: 38026480 Free PMC article.
-
Plasma Soluble Urokinase-Type Plasminogen Activator Receptor Level as a Predictor of the Severity of Community-Acquired Pneumonia.Int J Environ Res Public Health. 2019 Mar 21;16(6):1035. doi: 10.3390/ijerph16061035. Int J Environ Res Public Health. 2019. PMID: 30901954 Free PMC article.
-
Can Procalcitonin Add to the Prognostic Power of the Severity Scoring System in Adults with Pneumonia?Tanaffos. 2015;14(2):95-106. Tanaffos. 2015. PMID: 26528363 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous