Using stable isotope techniques in nutrition assessments and tracking of global targets post-2015
- PMID: 28347373
- DOI: 10.1017/S0029665117000295
Using stable isotope techniques in nutrition assessments and tracking of global targets post-2015
Abstract
Stable isotopes are non-radioactive, safe and are applied for various purposes in human health assessment in trace amounts that minimally disturb normal physiology. The International Atomic Energy Agency supports the use of stable isotope techniques to design and evaluate interventions addressing malnutrition in all its forms with focus on infant and young child feeding; maternal and adolescent nutrition; diet quality; prevention and control of non-communicable diseases; healthy ageing and gut function. These techniques can be used to objectively measure: (1) amount of human milk consumed and whether an infant is exclusively breastfed; (2) body composition in the context of re-feeding programmes for moderate and severe acute malnutrition and as an indicator of the risk for obesity; (3) bioavailability and bioconversion of pro-vitamin A and vitamin A body stores following vitamin A intervention programmes; (4) absorption and retention of iron, zinc and protein; (5) total energy expenditure for validation of physical activity measurement and dietary assessment tools and (6) diagnosis of Helicobacter pylori. Stable isotope techniques will be invaluable in the tracking of global targets on exclusive breast-feeding childhood obesity and anaemia among women. Efforts are underway to make nuclear techniques more affordable, field-friendly and less invasive, and to develop less sophisticated but precise equipment. Advocacy for the wide adoption of the techniques is needed.
Keywords: DD deuterium dilution EBF exclusive breast-feeding; EED environmental enteric dysfunction; FFM fat-free mass; IAEA International Atomic Energy Agency; IRMS isotope ratio mass spectrometer; International Atomic Energy Agency; Nutrition assessments; Stable isotopes.
Similar articles
-
Atoms for Nutrition: IAEA's Contribution to Tackling Malnutrition.J Nutr. 2023 Jan;153(1):10-16. doi: 10.1016/j.tjnut.2022.11.019. Epub 2022 Dec 22. J Nutr. 2023. PMID: 36913443
-
Use of Stable Isotopes to Evaluate Bioefficacy of Provitamin A Carotenoids, Vitamin A Status, and Bioavailability of Iron and Zinc.Adv Nutr. 2018 Sep 1;9(5):625-636. doi: 10.1093/advances/nmy036. Adv Nutr. 2018. PMID: 30239582 Free PMC article. Review.
-
'Dose-to-Mother' Deuterium Oxide Dilution Technique: An Accurate Strategy to Measure Vitamin A Intake in Breastfed Infants.Nutrients. 2017 Feb 21;9(2):169. doi: 10.3390/nu9020169. Nutrients. 2017. PMID: 28230781 Free PMC article.
-
Current Capabilities and Limitations of Stable Isotope Techniques and Applied Mathematical Equations in Determining Whole-Body Vitamin A Status.Food Nutr Bull. 2016 Jun;37(2 Suppl):S87-S103. doi: 10.1177/0379572116630642. Epub 2016 Apr 6. Food Nutr Bull. 2016. PMID: 27053491 Review.
-
Stable isotope dilution techniques for assessing vitamin A status and bioefficacy of provitamin A carotenoids in humans.Public Health Nutr. 2005 Sep;8(6):596-607. doi: 10.1079/phn2004715. Public Health Nutr. 2005. PMID: 16236189 Review.
Cited by
-
Relationship of body mass index to percent body fat determined by deuterium isotopic dilution and impedancemetry among Tunisian schoolchildren.Afr Health Sci. 2023 Sep;23(3):664-671. doi: 10.4314/ahs.v23i3.77. Afr Health Sci. 2023. PMID: 38357184 Free PMC article.
-
Body composition from birth to 2 years.Eur J Clin Nutr. 2023 Aug 10. doi: 10.1038/s41430-023-01322-7. Online ahead of print. Eur J Clin Nutr. 2023. PMID: 37563231 Review.
-
Birth Weight and Body Composition as Determined by Isotopic Dilution with Deuterium Oxide in 6- to 8-Year-Old South African Children.Children (Basel). 2022 Oct 21;9(10):1597. doi: 10.3390/children9101597. Children (Basel). 2022. PMID: 36291533 Free PMC article.
-
Dietary Intake and Energy Expenditure in Breast Cancer Survivors: A Review.Nutrients. 2021 Sep 27;13(10):3394. doi: 10.3390/nu13103394. Nutrients. 2021. PMID: 34684403 Free PMC article. Review.
-
Association between Objectively Determined Physical Activity Levels and Body Composition in 6-8-Year-Old Children from a Black South African Population: BC-IT Study.Int J Environ Res Public Health. 2021 Jun 15;18(12):6453. doi: 10.3390/ijerph18126453. Int J Environ Res Public Health. 2021. PMID: 34203654 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources