Clomipramine
- PMID: 30000234
- Bookshelf ID: NBK501175
Clomipramine
Excerpt
Limited evidence indicates that use of clomipramine during breastfeeding is acceptable. For women who were taking clomipramine during pregnancy, the amount of drug in breastmilk may be insufficient to prevent neonatal withdrawal symptoms in breastfed infants. A safety scoring system finds clomipramine to be possibly used with caution during breastfeeding.[1] For use as an antidepressant, clomipramine may be less desirable than other antidepressants that have been studied more thoroughly.
Similar articles
-
Carbamazepine.2022 Jun 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 Jun 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000330 Free Books & Documents. Review.
-
Oxcarbazepine.2021 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000302 Free Books & Documents. Review.
-
Imipramine.2022 Apr 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 Apr 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000239 Free Books & Documents. Review.
-
Desipramine.2022 Apr 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 Apr 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000238 Free Books & Documents. Review.
-
Trimipramine.2022 Apr 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 Apr 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000228 Free Books & Documents. Review.
References
-
- Uguz F. A new safety scoring system for the use of psychotropic drugs during lactation. Am J Ther. 2021;28:e118–e126. - PubMed
-
- Schimmell MS, Zylber Katz E, Shaag Y, et al. Toxic neonatal effects following maternal clomipramine therapy. J Toxicol Clin Toxicol. 1991;29:479–84. - PubMed
-
- Yoshida K, Smith B, Craggs M, et al. Investigation of pharmacokinetics and possible adverse effects in infants exposed to tricyclic antidepressants in breast-milk. J Affect Disord. 1997;43:225–37. - PubMed
-
- Khachman D, Gandia P, Gaillard MA, et al. Clomipramine in breast milk: A case study. J Pharm Clin. 2009;28:33–8. doi: 10.1684/jpc.2009.0112. - DOI
-
- Wisner KL, Perel JM, Foglia JP. Serum clomipramine and metabolite levels in four nursing mother-infant pairs. J Clin Psychiatry. 1995;56:17–20. - PubMed
Publication types
LinkOut - more resources
Full Text Sources