Giant hepatic hemangioma treatment with transcatheter arterial embolisation and transcatheter arterial chemoembolisation; Comparative results
- PMID: 34344145
- PMCID: PMC10734828
- DOI: 10.3906/sag-2102-352
Giant hepatic hemangioma treatment with transcatheter arterial embolisation and transcatheter arterial chemoembolisation; Comparative results
Abstract
Background/aim: Treatment of hepatic hemangiomas is a controversial topic, and traditional treatment is surgical excision. Transcatheter arterial embolisation (TAE) and transcatheter arterial chemoembolisation (TACE) have been reported as minimally invasive treatment methods. To the best of our knowledge, there are no studies comparing use of TACE and TAE for hepatic hemangioma treatment. The aim of the study is to compare symptom resolution, size reducing effects, and complications of TACE and TAE for the treatment of giant hepatic hemangiomas.
Materials and methods: A total of 104 patients underwent TACE using bleomycin, and 108 patients underwent TAE. The patients were followed-up for 2 year and follow-up images at 6 months, 12 months, and 24 months were acquired. Lesion volumes in both follow-up images were calculated. The patients were examined for any possible procedure related complications as well as the status of their initial symptoms.
Results: The shrinkage period was determined to have ended after 12. month in both groups. The results of the two-way mixed ANOVA showed that there was significant main effect of procedure type (p ≤ 0.001) on hemangioma volumes. Similarly, there was a significant interaction between procedure and time (p ≤ 0.001).
Conclusion: Both methods are effective in symptomatic relief in properly selected patients. However, TACE causes greater volume reduction with less pain and, therefore, is the better endovascular treatment option.
Keywords: Liver; angiography; bleomycin; embolization; hemangioma.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Conflict of interest statement
None declared.
Figures
![Figure 1](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/10734828/bin/turkjmedsci-51-6-2943f1.gif)
![Figure 2](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/10734828/bin/turkjmedsci-51-6-2943f2.gif)
![Figure 3](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/10734828/bin/turkjmedsci-51-6-2943f3.gif)
![Figure 4](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/10734828/bin/turkjmedsci-51-6-2943f4.gif)
Similar articles
-
Transarterial embolization with bleomycin-lipiodol emulsion: a successful minimal invasive approach for giant liver hemangioma.Clin J Gastroenterol. 2024 Jun;17(3):511-514. doi: 10.1007/s12328-024-01948-5. Epub 2024 Mar 25. Clin J Gastroenterol. 2024. PMID: 38526803
-
Transarterial (chemo)embolisation versus no intervention or placebo for liver metastases.Cochrane Database Syst Rev. 2020 Mar 12;3(3):CD009498. doi: 10.1002/14651858.CD009498.pub4. Cochrane Database Syst Rev. 2020. PMID: 32163181 Free PMC article.
-
Invasive management of symptomatic hepatic hemangioma.Eur J Gastroenterol Hepatol. 2019 Sep;31(9):1079-1084. doi: 10.1097/MEG.0000000000001413. Eur J Gastroenterol Hepatol. 2019. PMID: 31021878 Review.
-
Transarterial Bleomycin-Lipiodol Embolization (B/LE) for Symptomatic Giant Hepatic Hemangioma.Cardiovasc Intervent Radiol. 2018 Nov;41(11):1674-1682. doi: 10.1007/s00270-018-2010-4. Epub 2018 Jun 19. Cardiovasc Intervent Radiol. 2018. PMID: 29922860
-
Preoperative transcatheter arterial embolization for giant cavernous hemangioma of the liver with consumption coagulopathy.Am J Gastroenterol. 1997 Apr;92(4):688-91. Am J Gastroenterol. 1997. PMID: 9128326 Review.
Cited by
-
Hepatic Hemangioma: Review of Imaging and Therapeutic Strategies.Medicina (Kaunas). 2024 Mar 8;60(3):449. doi: 10.3390/medicina60030449. Medicina (Kaunas). 2024. PMID: 38541175 Free PMC article. Review.
-
Transarterial Bleomycin-Lipiodol Chemoembolization for the Treatment of Giant Hepatic Hemangiomas: An Assessment of Effectiveness.Cancers (Basel). 2024 Jan 16;16(2):380. doi: 10.3390/cancers16020380. Cancers (Basel). 2024. PMID: 38254869 Free PMC article.
-
Postnatal treatment and evolution patterns of giant fetal hepatic hemangioma: a case series of 29 patients.BMC Pediatr. 2024 Jan 3;24(1):8. doi: 10.1186/s12887-023-04476-2. BMC Pediatr. 2024. PMID: 38172842 Free PMC article.
-
Safety and Feasibility of Transarterial Bleomycin-Lipiodol Embolization in Patients with Giant Hepatic Hemangiomas.Medicina (Kaunas). 2023 Jul 25;59(8):1358. doi: 10.3390/medicina59081358. Medicina (Kaunas). 2023. PMID: 37629648 Free PMC article.
-
Kasabach-Merritt syndrome complicating a giant hemangioma of the liver: A case report.Radiol Case Rep. 2023 Apr 11;18(6):2183-2185. doi: 10.1016/j.radcr.2023.01.084. eCollection 2023 Jun. Radiol Case Rep. 2023. PMID: 37101891 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous