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Review
. 2024;22(1):6-15.
doi: 10.2174/011570162X282739231222062830.

The Interrelationship between HIV Infection and COVID-19: A Review of the Literature

Yiyu Wang  1 , Yu Lai  2
Affiliations
Review

The Interrelationship between HIV Infection and COVID-19: A Review of the Literature

Yiyu Wang et al. Curr HIV Res. 2024.

Abstract

The Corona Virus Disease 2019 (COVID-19) pandemic resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to significant morbidity and mortality in patients and put a strain on healthcare systems worldwide. The clinical characteristics and results of COVID-19 in immunosuppressed patients, such as people living with human immunodeficiency virus (PLWH), considered at higher risk of severe disease, are not well-characterized. Accumulated evidence indicates that COVID-19 and the human immunodeficiency virus (HIV) can interact in various ways. This review explored the similarities and differences in virology between SARS-CoV-2 and HIV, the effect of the COVID-19 vaccine on PLWH, the impact of the COVID-19 pandemic on PLWH care and prevention, and the influence of HIV-related factors on COVID-19. Discovering the potential link between HIV and COVID-19 may provide a novel way to avoid the factors of HIV and SARS-CoV-2 co-infection and advance future research.

Keywords: Coinfection; HIV; Keywords: COVID-19; PLWH; SARS-CoV-2; epidemic; virus.

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