Mental navigation along memorized routes activates the hippocampus, precuneus, and insula
- PMID: 9106758
- DOI: 10.1097/00001756-199702100-00032
Mental navigation along memorized routes activates the hippocampus, precuneus, and insula
Abstract
Positron emission tomography was used to investigate the functional anatomy of mental simulation of routes (MSR) in five normal volunteers. Normalized regional cerebral blood flow was measured while subjects mentally navigated between landmarks of a route which had been previously learned by actual navigation. This task was contrasted with both static visual imagery of landmarks (VIL) and silent Rest. MSR appears to be subserved by two distinct networks: a non-specific memory network including the posterior and middle parts of the hippocampal regions, the dorsolateral prefrontal cortex and the posterior cingulum, and a specific mental navigation network, comprising the left precuneus, insula and medial part of the hippocampal regions.
Similar articles
-
Knowing where and getting there: a human navigation network.Science. 1998 May 8;280(5365):921-4. doi: 10.1126/science.280.5365.921. Science. 1998. PMID: 9572740
-
Parietal and hippocampal contribution to topokinetic and topographic memory.Philos Trans R Soc Lond B Biol Sci. 1997 Oct 29;352(1360):1437-48. doi: 10.1098/rstb.1997.0130. Philos Trans R Soc Lond B Biol Sci. 1997. PMID: 9368932 Free PMC article. Review.
-
Noun and verb retrieval by normal subjects. Studies with PET.Brain. 1996 Feb;119 ( Pt 1):159-79. doi: 10.1093/brain/119.1.159. Brain. 1996. PMID: 8624678 Review.
-
Visual memory, visual imagery, and visual recognition of large field patterns by the human brain: functional anatomy by positron emission tomography.Cereb Cortex. 1995 Jan-Feb;5(1):79-93. doi: 10.1093/cercor/5.1.79. Cereb Cortex. 1995. PMID: 7719132 Clinical Trial.
-
Age-related reductions in human recognition memory due to impaired encoding.Science. 1995 Jul 14;269(5221):218-21. doi: 10.1126/science.7618082. Science. 1995. PMID: 7618082
Cited by
-
Common and specific activations supporting optic flow processing and navigation as revealed by a meta-analysis of neuroimaging studies.Brain Struct Funct. 2024 Jun;229(5):1021-1045. doi: 10.1007/s00429-024-02790-8. Epub 2024 Apr 9. Brain Struct Funct. 2024. PMID: 38592557 Free PMC article. Review.
-
Adult attention-deficit/hyperactivity disorder traits in healthy adults associated with brain volumetric data identify precuneus involvement in traffic crashes.Sci Rep. 2023 Dec 18;13(1):22466. doi: 10.1038/s41598-023-49907-3. Sci Rep. 2023. PMID: 38105321 Free PMC article.
-
A neural circuit for spatial orientation derived from brain lesions.Cereb Cortex. 2024 Jan 14;34(1):bhad486. doi: 10.1093/cercor/bhad486. Cereb Cortex. 2024. PMID: 38100330 Review.
-
Neurocognitive Adaptations for Spatial Orientation and Navigation in Astronauts.Brain Sci. 2023 Nov 15;13(11):1592. doi: 10.3390/brainsci13111592. Brain Sci. 2023. PMID: 38002551 Free PMC article.
-
Hippocampal-parietal cortex causal directed connectivity during human episodic memory formation: Replication across three experiments.bioRxiv [Preprint]. 2024 Mar 21:2023.11.07.566056. doi: 10.1101/2023.11.07.566056. bioRxiv. 2024. PMID: 37986855 Free PMC article. Preprint.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
