Authors
Christopher R Conner, Timothy M Ellmore, Michael A DiSano, Thomas A Pieters, Andrew W Potter, Nitin Tandon
Publication date
2011/12/1
Journal
Computers in biology and medicine
Volume
41
Issue
12
Pages
1100-1109
Publisher
Pergamon
Description
Here we present a novel multimodal analysis of network connectivity in the language system. We assessed connectivity of Broca's area using tractography with diffusion tensor imaging (DTI), and with cortico-cortical evoked potentials (CCEPs) to measure the spread of artificial currents applied directly to human cortex. We found that both the amplitude and latency of CCEP currents significantly correlates (r2=0.41, p<10−16) with the number of DTI pathways connecting the stimulation and recording loci. This strategy of relating electrical information flow with the neural architecture will likely yield new insights into cognitive processes.
Total citations
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Scholar articles
CR Conner, TM Ellmore, MA DiSano, TA Pieters… - Computers in biology and medicine, 2011