All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Protease inhibitors

Introduction

Protease inhibitors are molecules that inhibit the function of proteases, and many naturally occurring protease inhibitors are proteins. Protease inhibitors can be used as antiviral drugs and the FDA has approved the marketing of 7 protease inhibitor drugs including SQV, RTV, IDV, NFV, and APV, etc.

Protease inhibitors are further categorized into serine protease inhibitors, cysteine protease inhibitors, aspartate protease inhibitors, and metalloproteinase inhibitors based on homology of amino acid sequences and target proteases. Mutations in the key amino acids of proteases and their inhibitors can affect their physiological functions, stability, catalytic activity, inhibitory specificity, and so on.

It has become one of the current hotspots to explore various mutants of proteases and their inhibitors in nature, analyze their key active sites, and use protein engineering to modify and design proteases and their inhibitors with stronger activity, higher stability, better specificity, more environmentally friendly, and lower cost.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF017-M02	OC-HPI-M02	Human	154	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF017-M35	OC-HPI-M35	Human	154	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF017-M98	OC-HPI-M98	Human	154	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF017-Lv105	OC-HPI-Lv105	Human	154	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF017-Lv242	OC-HPI-Lv242	Human	154	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF017-GC	OC-HPI-GC	Human	154	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
SERPINA4	NM_006215.2	Human	Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SERPINA4), mRNA.	1284	GC-F0947
SERPINB3	NM_006919.1	Human	Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 3 (SERPINB3), mRNA.	1173	GC-Z7649
SERPINH1	NM_001235.5	Human	Homo sapiens serpin family H member 1 (SERPINH1), transcript variant 2, mRNA.	1257	GC-H9437
XIAP	NM_001167.4	Human	Homo sapiens X-linked inhibitor of apoptosis (XIAP), transcript variant 1, mRNA.	1494	GC-H4489
SERPINA4	NM_006215.1	Human	Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SERPINA4), mRNA.	1284	GC-Z9363
A2M	NM_000014.5	Human	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.	4425	GC-A3521
SERPING1	NM_000062.3	Human	Homo sapiens serpin family G member 1 (SERPING1), transcript variant 1, mRNA.	1503	GC-A3230
C3	NM_000064.4	Human	Homo sapiens complement C3 (C3), mRNA.	4992	GC-E2587
COL4A3	NM_000091.5	Human	Homo sapiens collagen type IV alpha 3 chain (COL4A3), mRNA.	5013	GC-A3980
CSTB	NM_000100.4	Human	Homo sapiens cystatin B (CSTB), mRNA.	297	GC-F0136
SERPIND1	NM_000185.4	Human	Homo sapiens serpin family D member 1 (SERPIND1), mRNA.	1500	GC-G0094
ANOS1	NM_000216.4	Human	Homo sapiens anosmin 1 (ANOS1), mRNA.	2043	GC-Y5283
SERPINA7	NM_000354.6	Human	Homo sapiens serpin family A member 7 (SERPINA7), mRNA.	1248	GC-T1279
TIMP3	NM_000362.5	Human	Homo sapiens TIMP metallopeptidase inhibitor 3 (TIMP3), mRNA.	636	GC-F0898
HRG	NM_000412.5	Human	Homo sapiens histidine rich glycoprotein (HRG), mRNA.	1578	GC-G0140
APP	NM_000484.4	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.	2313	GC-Z2553
SERPINC1	NM_000488.4	Human	Homo sapiens serpin family C member 1 (SERPINC1), transcript variant 1, mRNA.	1395	GC-F0358
GPX1	NM_000581.4	Human	Homo sapiens glutathione peroxidase 1 (GPX1), transcript variant 1, mRNA.	612	GC-Z2571
SERPINE1	NM_000602.5	Human	Homo sapiens serpin family E member 1 (SERPINE1), transcript variant 2, mRNA.	1209	GC-F0606
ITIH5	NM_001001851.3	Human	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 5 (ITIH5), transcript variant 3, mRNA.	2109	GC-Z4015
C4B	NM_001002029.4	Human	Homo sapiens complement C4B (Chido blood group) (C4B), mRNA.	5235	GC-E2592
CST9	NM_001008693.3	Human	Homo sapiens cystatin 9 (CST9), mRNA.	480	GC-H3350
BIRC5	NM_001012270.2	Human	Homo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2, mRNA.	414	GC-Z3551
SERPINI2	NM_001012303.2	Human	Homo sapiens serpin family I member 2 (SERPINI2), transcript variant 1, mRNA.	1248	GC-Z1321
SERPINB8	NM_001031848.2	Human	Homo sapiens serpin family B member 8 (SERPINB8), transcript variant 3, mRNA.	729	GC-Z2013
COL28A1	NM_001037763.3	Human	Homo sapiens collagen type XXVIII alpha 1 chain (COL28A1), mRNA.	3378	GC-A4237
SPINK13	NM_001040129.3	Human	Homo sapiens serine peptidase inhibitor Kazal type 13 (SPINK13), transcript variant 1, mRNA.	285	GC-H0478
SPOCK3	NM_001040159.2	Human	Homo sapiens SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 (SPOCK3), transcript variant 1, mRNA.	1302	GC-Z3167
SPINK9	NM_001040433.2	Human	Homo sapiens serine peptidase inhibitor Kazal type 9 (SPINK9), mRNA.	261	GC-H0726
CAST	NM_001042443.3	Human	Homo sapiens calpastatin (CAST), transcript variant 9, mRNA.	2127	GC-H3424
CAST	NM_001042444.3	Human	Homo sapiens calpastatin (CAST), transcript variant 10, mRNA.	2004	GC-T9667
SERPINA11	NM_001080451.2	Human	Homo sapiens serpin family A member 11 (SERPINA11), mRNA.	1269	GC-H0143
SERPINA3	NM_001085.5	Human	Homo sapiens serpin family A member 3 (SERPINA3), transcript variant 1, mRNA.	1272	GC-A3443
KNG1	NM_001102416.3	Human	Homo sapiens kininogen 1 (KNG1), transcript variant 1, mRNA.	1935	GC-H2841
HMSD	NM_001123366.2	Human	Homo sapiens histocompatibility minor serpin domain containing (HMSD), mRNA.	420	GC-H3031
LEF1	NM_001130713.3	Human	Homo sapiens lymphoid enhancer binding factor 1 (LEF1), transcript variant 2, mRNA.	1116	GC-Z6436
LEF1	NM_001130714.3	Human	Homo sapiens lymphoid enhancer binding factor 1 (LEF1), transcript variant 3, mRNA.	1161	GC-T9411
APP	NM_001136016.3	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 4, mRNA.	2241	GC-Z6606
APP	NM_001136130.3	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.	2145	GC-Z6628
APP	NM_001136131.3	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 7, mRNA.	1983	GC-Z6629
SERPINE2	NM_001136528.2	Human	Homo sapiens serpin family E member 2 (SERPINE2), transcript variant 2, mRNA.	1194	GC-H3928
APLP2	NM_001142278.2	Human	Homo sapiens amyloid beta precursor like protein 2 (APLP2), transcript variant 4, mRNA.	1569	GC-Y4654
SERPINB2	NM_001143818.2	Human	Homo sapiens serpin family B member 2 (SERPINB2), transcript variant 1, mRNA.	1248	GC-Z6805
SNCA	NM_001146055.2	Human	Homo sapiens synuclein alpha (SNCA), transcript variant 3, mRNA.	423	GC-G0543
CD109	NM_001159587.3	Human	Homo sapiens CD109 molecule (CD109), transcript variant 2, mRNA.	4287	GC-E2721
CD109	NM_001159588.3	Human	Homo sapiens CD109 molecule (CD109), transcript variant 3, mRNA.	4107	GC-E2722
GPC3	NM_001164617.2	Human	Homo sapiens glypican 3 (GPC3), transcript variant 1, mRNA.	1812	GC-Z7351
GPC3	NM_001164618.2	Human	Homo sapiens glypican 3 (GPC3), transcript variant 3, mRNA.	1695	GC-Z7352
GPC3	NM_001164619.2	Human	Homo sapiens glypican 3 (GPC3), transcript variant 4, mRNA.	1581	GC-Z7353
LEF1	NM_001166119.2	Human	Homo sapiens lymphoid enhancer binding factor 1 (LEF1), transcript variant 4, mRNA.	912	GC-Z8796