Journal Description
Cosmetics
Cosmetics
is an international, scientific, peer-reviewed, open access journal on the science and technology of cosmetics published bimonthly online by MDPI.
- Open Access— free for readers, with article processing charges (APC) paid by authors or their institutions.
- High Visibility: indexed within Scopus, ESCI (Web of Science), CAPlus / SciFinder, and other databases.
- Journal Rank: JCR - Q2 (Dermatology) / CiteScore - Q1 (Surgery)
- Rapid Publication: manuscripts are peer-reviewed and a first decision is provided to authors approximately 18 days after submission; acceptance to publication is undertaken in 6.6 days (median values for papers published in this journal in the second half of 2023).
- Recognition of Reviewers: reviewers who provide timely, thorough peer-review reports receive vouchers entitling them to a discount on the APC of their next publication in any MDPI journal, in appreciation of the work done.
Impact Factor:
3.4 (2023)
Latest Articles
Artificial Intelligence in Plastic Surgery: Advancements, Applications, and Future
Cosmetics 2024, 11(4), 109; https://doi.org/10.3390/cosmetics11040109 - 27 Jun 2024
Abstract
Artificial intelligence (AI) is revolutionizing plastic surgery through its remarkable advancements in various domains such as image analysis, robotic assistance, predictive analytics, and augmented reality. Predictive analytics, powered by AI, harnesses patient data to predict surgical outcomes, minimize risks, and tailor treatment plans,
[...] Read more.
Artificial intelligence (AI) is revolutionizing plastic surgery through its remarkable advancements in various domains such as image analysis, robotic assistance, predictive analytics, and augmented reality. Predictive analytics, powered by AI, harnesses patient data to predict surgical outcomes, minimize risks, and tailor treatment plans, thereby optimizing patient care and safety. Augmented reality and virtual reality technology are also reshaping the cosmetic surgery landscape, providing immersive experiences for preoperative imaging, intraoperative guidance, and advanced skills through simulation. Looking ahead, the future of AI in plastic surgery holds great promise, including personalized medicine, bioprinting of tissues and organs, and continuous learning through iterative improvement algorithms based on real-world surgical experience. However, amid these transformational advances, ethical considerations and regulatory frameworks must evolve to ensure the responsible deployment of AI, protect patient privacy, minimize errors and algorithmic deviation, and uphold standards of fairness and transparency. Our study aims to explore the role of AI in the field of plastic surgery with the potential for the future in mind. In summary, AI is considered a beacon of innovation in plastic surgery, enhancing surgical precision, enhancing patient outcomes, and heralding a future where interventions rely on personalized technology that will redefine the boundaries of aesthetic and regenerative medicine.
Full article
Open AccessReview
Examining How Diet and Lifestyle Influence Skin Appearance through a Common Risk Factor: Excess Iron—A Comprehensive Review
by
Tianshu Yang, Lungchi Chen and Xi Huang
Cosmetics 2024, 11(4), 108; https://doi.org/10.3390/cosmetics11040108 - 27 Jun 2024
Abstract
In the contemporary era, youthful and healthy skin is a pivotal determinant of beauty. Choices pertaining to one’s dietary and lifestyle practices wield substantial influence over skin health. Currently, the focal point of attention lies in strategies that delay skin aging and maintain
[...] Read more.
In the contemporary era, youthful and healthy skin is a pivotal determinant of beauty. Choices pertaining to one’s dietary and lifestyle practices wield substantial influence over skin health. Currently, the focal point of attention lies in strategies that delay skin aging and maintain skin quality. Remarkably, the skin, the body’s largest organ, serves as the primary defense barrier against external elements. Skin aging encompasses intrinsic and extrinsic categories, both susceptible to genetic, lifestyle, and environmental factors. Given the strides in science and technology, the pursuit of effective and safe interventions for skin aging assumes paramount importance. Thus, this review delves into the intricate relationship between diet, lifestyle, and skin aging, culminating in an exploration of the crucial role played by excess iron in this intricate nexus. Understanding these dynamics holds promise for advancing our knowledge of skincare and the quest for timeless vitality.
Full article
(This article belongs to the Special Issue Chinese American Cosmetic Professional Association (CACPA)—a Collaborative and Inclusive Platform for Research and Education of Cosmetic and Personal Care Products)
Open AccessArticle
Extending the Physical Functionality of Bioactive Blends of Astrocaryum Pulp and Kernel Oils from Guyana
by
Laziz Bouzidi, Shaveshwar Deonarine, Navindra Soodoo, R. J. Neil Emery, Sanela Martic and Suresh S. Narine
Cosmetics 2024, 11(4), 107; https://doi.org/10.3390/cosmetics11040107 - 26 Jun 2024
Abstract
Natural lipids with nutritional or therapeutic benefits that also provide desired texture, melting and organoleptic appeal (mouthfeel, skin feel) are difficult to procure for the food and cosmetics industries. Natural Astrocaryum pulp oil (AVP) and kernel fat (AVK) from Guyana were blended without
[...] Read more.
Natural lipids with nutritional or therapeutic benefits that also provide desired texture, melting and organoleptic appeal (mouthfeel, skin feel) are difficult to procure for the food and cosmetics industries. Natural Astrocaryum pulp oil (AVP) and kernel fat (AVK) from Guyana were blended without further modification to study the potential of extending the physical functionality of the blends beyond that of crude AVK and AVP. An evaluation of non-lipid components by ESI-MS indicated twenty-four (24) bioactive molecules, mainly carotenoids (90%), polyphenols (9%) and sterols (1%) in AVP, indicating important health and therapeutic benefits. Only trace-to-negligible amounts of these compounds were detected in AVK. The thermal transition phase behavior, solid fat content (SFC), microstructure and textural properties of five AVP/AVL blends were used to construct phase diagrams of the AVK/AVP binary system. Binary phase diagrams constructed from the cooling and heating DSC thermograms of the mixtures and description of the liquidus line indicated a mixing behavior close to ideal with a tendency for order, with no phase separation. Melting onsets, solid fat content and measurements of solid-like texture all predictively increased with increasing AVK content. The descriptive decay parameters obtained for SFC, crystal size, hardness, firmness and spreadability were similar and predictive and indicate the way the binary system structure approaches that of a liquid or a functional solid. The bioactive content of the blends was accurately calculated; the work provides a blueprint for the blending of AVP and AVK to deliver targeted bioactive content, stability, spreadability, texture, melting profile, organoleptic appeal and solid content. SFCs at 20 °C ranged from 9.1% to 39.1%, melting onset from −17.5 °C to 27.8 °C, hardness from 0.1 N to 3.5 N and spreadability from 3.3 N·s to 147.1 N·s; indicating a useful dynamic range of physical properties suitable for bioactive oils to bioactive butters.
Full article
(This article belongs to the Special Issue Application of Plant-Based Molecules and Materials in Cosmetics)
Open AccessArticle
The Influence of Physical Characteristics of Wet Wipe Fabrics on the Microbial Biomass Accumulation
by
Noa Ziklo, Idit Yuli, Maayan Bibi and Paul Salama
Cosmetics 2024, 11(4), 106; https://doi.org/10.3390/cosmetics11040106 - 26 Jun 2024
Abstract
The physicochemical properties of nonwoven wet wipe fabrics have a strong influence on the ability of microorganisms to attach and multiply, until a biofilm is formed. Cellulose-based fabrics, being biodegradable, represent a major contamination risk. In addition, having a hydrophilic nature, they provide
[...] Read more.
The physicochemical properties of nonwoven wet wipe fabrics have a strong influence on the ability of microorganisms to attach and multiply, until a biofilm is formed. Cellulose-based fabrics, being biodegradable, represent a major contamination risk. In addition, having a hydrophilic nature, they provide a good platform for microorganisms attachment. To optimize biodegradable wet wipes antimicrobial quality, it is crucial to assess the impact of physicochemical properties, e.g., density, pore size, fiber diameter, contact angle and surface charge. Here, we investigated the physical characteristics of commonly used nonwoven fabrics from both synthetic (Polyethylene terephthalate, PET) and natural components (wood pulp and viscose), to evaluate their effect on microbial contamination. We found that the hydrophobicity of the fabric had varying influence on attachment, depending on the microbial strain. However, the geometry, as well as the fabric pore size greatly affected attachment regardless of the microbial strain, in which a larger pore size resulted in lower accumulation of microbial biomass. Our study gives insight into the characteristics of wet wipes that can affect the preservation efficacy and microbial contamination risk, in one of the biggest segments in the personal care industry.
Full article
Open AccessArticle
The Inhibition of Oxidative Stress-Mediated Cell Apoptosis by the Caspase Inhibitor (S)-3-((S)-2-(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-oxoisoindolin-2-yl)butanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic Acid in Human Dermal Papilla Cells
by
Bomi Park, Daeun Kim, Yurim Lee, Seihyun Choi, HeeDong Park, Sanghwa Lee and Jaesung Hwang
Cosmetics 2024, 11(4), 105; https://doi.org/10.3390/cosmetics11040105 - 22 Jun 2024
Abstract
Alopecia is traditionally viewed as androgen-dependent, but emerging evidence has implicated oxidative stress in the pathogenesis of hair loss. Current treatments for alopecia have limited efficacy, leading to the need for new therapies. Human dermal papilla cells (hDPCs) play a pivotal role in
[...] Read more.
Alopecia is traditionally viewed as androgen-dependent, but emerging evidence has implicated oxidative stress in the pathogenesis of hair loss. Current treatments for alopecia have limited efficacy, leading to the need for new therapies. Human dermal papilla cells (hDPCs) play a pivotal role in hair follicle (HF) development and hair growth regulation. In this study, we investigated the potential of (S)-3-((S)-2-(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-oxoisoindolin-2-yl)butanamido)-4-oxo-5-(2,3,5,6 tetrafluorophenoxy) pentanoic acid (THPA), a pan-caspase inhibitor, to reduce ROS-induced cellular damage and apoptosis in hDPCs. Our study revealed that THPA effectively suppressed hydrogen peroxide-induced apoptosis while also attenuating activated caspase signaling. Additionally, THPA restored the down-regulated expression of β-catenin, a key mediator of the Wnt/β-catenin pathway, in hDPCs exposed to hydrogen peroxide. Furthermore, significant alterations in Akt/mTOR/p70S6K signaling were observed following THPA treatment. Notably, THPA treatment led to a reduction in the expression of Dickkopf-1 (DKK-1), an inhibitor of the Wnt/β-catenin pathway implicated in hair follicle regression. Moreover, THPA treatment decreased the expression of the cell senescence markers p21 and p16, suggesting a potential role in preserving hDPC function and delaying hair follicle regression. Collectively, our findings highlight the therapeutic potential of THPA in preventing hair loss by protecting hDPCs against oxidative stress damage.
Full article
(This article belongs to the Special Issue Current and Future Trends in Cosmetics Research: The 10th Anniversary of Cosmetics)
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Open AccessArticle
Development of an Antioxidant, Anti-Aging, and Photoprotective Phytocosmetic from Discarded Agave sisalana Perrine Roots
by
Guilherme dos Santos Mazo, Julia Amanda Rodrigues Fracasso, Luísa Taynara Silvério da Costa, Valdecir Farias Ximenes, Natália Alves Zoppe, Amanda Martins Viel, Lucas Pires Guarnier, Beatriz de Castro Silva, Luan Victor Coelho de Almeida and Lucinéia dos Santos
Cosmetics 2024, 11(3), 104; https://doi.org/10.3390/cosmetics11030104 - 20 Jun 2024
Abstract
The primary source of hard fiber globally is Agave sisalana Perrine, also known as sisal. In areas where sisal is grown, the roots of the plant are usually left in the field after it has stopped producing, which leads to soil degradation and
[...] Read more.
The primary source of hard fiber globally is Agave sisalana Perrine, also known as sisal. In areas where sisal is grown, the roots of the plant are usually left in the field after it has stopped producing, which leads to soil degradation and decreased sisal productivity. It is, therefore, critical to find alternatives to reuse this waste. This study explores the potential use of sisal waste in the cosmetic industry by incorporating a hydroethanolic extract (HER) into a cream–gel formulation, taking advantage of the plant’s recognized ethnopharmacological value. The study involves analyzing the extract’s phytochemical composition (flavonoids) and evaluating its cytotoxicity. Subsequently, the antioxidant and antiglycation activities of the extract and cream–gel are evaluated, as well as ex vivo ocular toxicity, photoprotective activity, and preliminary stability analyses. The HER extract showed a flavonoid composition (catechin, kaempferol, isorhamnetin, and chrysin) and maintained cell viability above 70% throughout all time points analyzed in the MTT assay. Furthermore, the extract and the formulation demonstrated proven antioxidant and antiglycation activities. The cream–gel’s UVB and UVA protection effectiveness with the HER was comparable to that of synthetic UVB/UVA sunscreens, with the samples proving nonirritating and stable. In conclusion, the extract has a significant presence of flavonoids, and the cream–gel developed with it did not present cytotoxicity and met the stability requirements, indicating phytocosmetic potential with antioxidant, antiglycation, and photoprotective properties.
Full article
(This article belongs to the Special Issue Natural Sources for Cosmetic Ingredients: Challenges and Innovations)
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Open AccessArticle
Establishing the Inhibition of the Serine Protease Plasmin as a Skin Anti-Aging Pathway
by
Remo Campiche, Dominik Imfeld, Chennakesava Cuddapah, Leithe Budel and Mathias Gempeler
Cosmetics 2024, 11(3), 103; https://doi.org/10.3390/cosmetics11030103 - 19 Jun 2024
Abstract
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Plasmin is a serine protease induced by UV-irradiation in skin that contributes to inflammation. We showed that plasmin is upregulated in photo-exposed facial skin and that this correlates with increased transepidermal water loss (TEWL). Plasmin activity upregulates downstream pathways such as pro-inflammatory cytokines
[...] Read more.
Plasmin is a serine protease induced by UV-irradiation in skin that contributes to inflammation. We showed that plasmin is upregulated in photo-exposed facial skin and that this correlates with increased transepidermal water loss (TEWL). Plasmin activity upregulates downstream pathways such as pro-inflammatory cytokines and matrix-metalloproteinases (MMPs). In addition, the plasminogen system modulates cutaneous melanogenesis. In this study, we investigated potential skin-aging effects of plasmin with a dual inhibitor of plasmin and its activator urokinase (uPA). We established a range of in vitro and ex vivo assays to investigate inflammation, MMP-9 activation, and collagen modulation, and the melanogenesis modulation activity of plasmin. A specific plasmin inhibitor, Amidinobenzyl Benzylsulfonyl D-Seryl Homophenylalaninamide Acetate (ABSHA), was used in these assays to downregulate these effects. We found that ABSHA was able to down-regulate UV-irradiation-induced MMP-9 expression, and subsequent collagen IV degradation, ex vivo. In addition, the increased melanin synthesis in epidermal melanocytes was reduced significantly by ABSHA. Furthermore, dermal fibroblasts treated with the plasmin inhibitor showed increased collagen I synthesis. We further investigated these effects in a two-month, monocentric, placebo-controlled human study on female Chinese volunteers. We found a significant increase in collagen density by ultrasound measurement and an increase in elasticity by cutometer assessment in the group using a formulation consisting of a 10 ppm ABSHA solution. This resulted in decreased wrinkle volumes on both the forehead and crow’s feet as shown by Primos CR. Looking at age spots, there was a decrease in overall ITA° and melanin density as well as in the total age spot area. Our results establish plasmin as a skin-aging enzyme. Using specific inhibitors against plasmin shows promise against age-induced skin conditions.
Full article
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Open AccessArticle
Exploring the Use of Natural Ingredients for the Protection of Textured Hair from Ultraviolet Radiation: An In Vitro Study
by
Ewa Markiewicz and Olusola C. Idowu
Cosmetics 2024, 11(3), 102; https://doi.org/10.3390/cosmetics11030102 - 19 Jun 2024
Abstract
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Human hair is characterized by significant diversity, which is dictated by the individual genetic makeup. It is estimated that up to 70% of the world’s population has textured hair, with a significant proportion also living in areas with high exposure to ultraviolet radiation
[...] Read more.
Human hair is characterized by significant diversity, which is dictated by the individual genetic makeup. It is estimated that up to 70% of the world’s population has textured hair, with a significant proportion also living in areas with high exposure to ultraviolet radiation (UVR). This highlights the unique requirements for textured hair care products that can protect hair shafts from the harmful effects of the environment whilst enhancing the natural features of the fibre. In this study, we investigated the UV-protective effects of hair conditioner formulated from active ingredients, mangiferin, ferulic acid and naringin. The analysis of UV-irradiated straight and textured hair was performed by measurements of hair thickness and darkness, the uptake of the fluorescent dye, spectral absorbance of keratin extracts, ATR-FTIR and SEM. We found that textured hair was more sensitive to UVR-induced changes than straight hair, with the primary molecular targets represented by chemical groups in keratins. Pre-treatment of the hair with conditioner had protective effects against structural damage and oxidative stress caused by UVR. These data indicate the importance of the personalized approach to hair research and the formulation of hair care products tailored to the individual demands of textured hair types.
Full article
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Open AccessArticle
Effects of CE Ferulic® Combined with Microneedling in the Treatment of Pigmentary Disorders: A Monocentric, Split Face, Comparative Study
by
Ilaria Proietti, Stefania Guida, Agnieszka Dybala, Alessandra Spagnoli and Concetta Potenza
Cosmetics 2024, 11(3), 101; https://doi.org/10.3390/cosmetics11030101 - 17 Jun 2024
Abstract
Pigmentary disorders of the face present a significant challenge in dermatology, impacting the confidence and well-being of affected individuals. Various approaches have been developed to address these concerns, including microneedling and topical vitamin C products. This study involved 15 participants undergoing three treatment
[...] Read more.
Pigmentary disorders of the face present a significant challenge in dermatology, impacting the confidence and well-being of affected individuals. Various approaches have been developed to address these concerns, including microneedling and topical vitamin C products. This study involved 15 participants undergoing three treatment sessions over 12 weeks, assessing the efficacy of a combined microneedling and CE Ferulic® serum approach. Clinical evaluation and statistical analysis were conducted before and after the intervention. Significant improvement of akin hyperpigmentation was observed, particularly on the side treated with microneedling and CE Ferulic® serum compared to microneedling alone. The integrated treatment protocol demonstrated a synergistic effect in improving skin texture and appearance. Integrated treatment protocols, such as combining microneedling with CE Ferulic® serum, show promise in managing facial hyperpigmentation disorders. Further research with larger cohorts is warranted to validate these findings and optimize treatment strategies, highlighting the potential of combined therapeutic modalities for achieving optimal clinical outcomes in pigmentary disorder management.
Full article
(This article belongs to the Special Issue New Advances in Medical and Cosmetic Dermatology)
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Open AccessArticle
A Split-Face Comparison of Novel Microneedle Patch versus Botulinum Toxin-A and Microneedle Patch for Improvement in Undereye Skin Texture
by
Polen Te, Jitlada Meephansan, Punyaphat Sirithanabadeekul, Purit Pureesrisak, Kittipong Tantisantisom, Sattra Thongma, Yossawat Rayanasukha, Punyanuch Adulyaritthikul and Paisan Khanchaitit
Cosmetics 2024, 11(3), 100; https://doi.org/10.3390/cosmetics11030100 - 17 Jun 2024
Abstract
(1) Background: The emergence of microneedle patch technology and its development as a transdermal drug delivery platform have shown proven results in improving skin texture and appearance. This study was conducted to determine the efficacy of the microneedle patch (MNP)-only cosmesis of undereye
[...] Read more.
(1) Background: The emergence of microneedle patch technology and its development as a transdermal drug delivery platform have shown proven results in improving skin texture and appearance. This study was conducted to determine the efficacy of the microneedle patch (MNP)-only cosmesis of undereye skin texture and wrinkles against patch cosmesis with diluted botulinum toxin-A. (2) Methods: A total of 23 Thai females volunteered for this prospective clinical trial. Each participant was treated according to a split-face design, with the application of diluted botulinum toxin-A through MNP technology to the right undereye and a normal saline MNP application to the left undereye. Test areas were recorded at baseline and 2, 4, 8, 12, and 16 weeks after the initial treatment. (3) Results: Botulinum toxin-A was successfully delivered to the skin by MNP technology. After the initial treatment, these novel transdermal drug delivery patches significantly improved infraorbital hollowness at week 8 and wrinkles at week 16. In addition, the skin surface was markedly enhanced, with no adverse effects observed during the trial. (4) Conclusions: Novel MNPs are an effective and safe technology for use in the management of undereye skin aging. Combination treatment with botulinum toxin-A-impregnated devices gave a higher patient satisfaction than MNPs alone.
Full article
(This article belongs to the Special Issue Advanced Delivery Systems for Dermatologic and Dermocosmetics Products)
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