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Heart valve regurgitation

MedGen UID:
538923
Concept ID:
C0264879
Pathologic Function
Synonyms: Cardiac valve insufficiency; Valvular insufficiency
SNOMED CT: Heart valve regurgitation (40445007); Heart valve insufficiency (40445007); Heart valve incompetence (40445007)

Definition

Regurgitation of the blood of the heart valves owning to imperfect closing, insufficiency or incompetency of the valves. [from NCI]

Professional guidelines

PubMed

Lund MB, Kongerud J, Boe J, Nome O, Abrahamsen AF, Ihlen H, Forfang K
Ann Oncol 1996 Mar;7(3):257-64. doi: 10.1093/oxfordjournals.annonc.a010569. PMID: 8740789

Recent clinical studies

Etiology

He YS, Yang M, Liu G, Ji J, Qian SY
Pediatr Pulmonol 2023 Jul;58(7):2017-2024. Epub 2023 Apr 26 doi: 10.1002/ppul.26426. PMID: 37098833
Fragasso G, Sanvito F, Monaca G, Ardizzone V, De Bonis M, Pappalardo F, Smart C, Montanaro C, Lapenna E, Calabrese MC, Castiglioni A, Benussi S, Maisano F, Zangrillo A, Ambrosi A, Doglioni C, Alfieri O, Margonato A
J Cardiovasc Med (Hagerstown) 2022 Aug 1;23(8):505-512. doi: 10.2459/JCM.0000000000001347. PMID: 35904996
Nielsen HH, Egeblad H, Andersen HR, Thuesen L, Poulsen SH, Klaaborg KE, Jakobsen CJ, Hjortdal VE
Scand Cardiovasc J Suppl 2013 Feb;47(1):36-41. Epub 2012 Oct 15 doi: 10.3109/14017431.2012.731519. PMID: 22989057
Corvol JC, Anzouan-Kacou JB, Fauveau E, Bonnet AM, Lebrun-Vignes B, Girault C, Agid Y, Lechat P, Isnard R, Lacomblez L
Arch Neurol 2007 Dec;64(12):1721-6. doi: 10.1001/archneur.64.12.1721. PMID: 18071034
Mast ST, Gersing KR, Anstrom KJ, Krishnan KR, Califf RM, Jollis JG
Am J Cardiol 2001 Apr 15;87(8):989-93: A4. doi: 10.1016/s0002-9149(01)01435-7. PMID: 11305992

Diagnosis

Vermersch M, Longère B, Coisne A, Schmidt M, Forman C, Monnet A, Pagniez J, Silvestri V, Simeone A, Cheasty E, Montaigne D, Pontana F
Eur Radiol 2020 Jan;30(1):609-619. Epub 2019 Aug 1 doi: 10.1007/s00330-019-06341-2. PMID: 31372784
Ennezat PV, Bruneval P, Czitrom D, Gueffet JP, Piriou N, Trochu JN, Patra O, Blanchard-Lemoine B, du Fretay XH, Nazeyrollas P, Assoun B, Jobic Y, Brochet E, Bogino E, Roudaut R, Augier C, Greffe L, Petit-Eisenmann H, Dambrin C, Chavanon O, Guillou L, Grisoli D, Morera P, Banfi C, Remadi JP, Fabre O, Vincentelli A, Lantuejoul S, Ikoli JF, Copin MC, Malergue MC, Maréchaux S, Tribouilloy C
Int J Cardiol 2016 Oct 1;220:429-34. Epub 2016 Jun 23 doi: 10.1016/j.ijcard.2016.06.112. PMID: 27390966
Eren E, Ellidag HY, Cekin Y, Ayoglu RU, Sekercioglu AO, Yılmaz N
Redox Rep 2014 Jan;19(1):34-9. Epub 2013 Nov 26 doi: 10.1179/1351000213Y.0000000069. PMID: 24192717Free PMC Article
Tribouilloy C, Maréchaux S, Jobic Y, Jeu A, Ederhy S, Donal E, Réant P, Arnalsteen E, Boulanger J, Garban T, Ennezat PV, Andréjak M, Rusinaru D
Eur Heart J 2013 Dec;34(46):3580-7. Epub 2013 Sep 6 doi: 10.1093/eurheartj/eht266. PMID: 24014218
Lund MB, Ihlen H, Voss BM, Abrahamsen AF, Nome O, Kongerud J, Stugaard M, Forfang K
Heart 1996 Jun;75(6):591-5. doi: 10.1136/hrt.75.6.591. PMID: 8697163Free PMC Article

Therapy

He YS, Yang M, Liu G, Ji J, Qian SY
Pediatr Pulmonol 2023 Jul;58(7):2017-2024. Epub 2023 Apr 26 doi: 10.1002/ppul.26426. PMID: 37098833
Nielsen HH, Egeblad H, Andersen HR, Thuesen L, Poulsen SH, Klaaborg KE, Jakobsen CJ, Hjortdal VE
Scand Cardiovasc J Suppl 2013 Feb;47(1):36-41. Epub 2012 Oct 15 doi: 10.3109/14017431.2012.731519. PMID: 22989057
Vallette S, Serri K, Rivera J, Santagata P, Delorme S, Garfield N, Kahtani N, Beauregard H, Aris-Jilwan N, Houde G, Serri O
Pituitary 2009;12(3):153-7. doi: 10.1007/s11102-008-0134-2. PMID: 18594989
Corvol JC, Anzouan-Kacou JB, Fauveau E, Bonnet AM, Lebrun-Vignes B, Girault C, Agid Y, Lechat P, Isnard R, Lacomblez L
Arch Neurol 2007 Dec;64(12):1721-6. doi: 10.1001/archneur.64.12.1721. PMID: 18071034
Mast ST, Gersing KR, Anstrom KJ, Krishnan KR, Califf RM, Jollis JG
Am J Cardiol 2001 Apr 15;87(8):989-93: A4. doi: 10.1016/s0002-9149(01)01435-7. PMID: 11305992

Prognosis

Fragasso G, Sanvito F, Monaca G, Ardizzone V, De Bonis M, Pappalardo F, Smart C, Montanaro C, Lapenna E, Calabrese MC, Castiglioni A, Benussi S, Maisano F, Zangrillo A, Ambrosi A, Doglioni C, Alfieri O, Margonato A
J Cardiovasc Med (Hagerstown) 2022 Aug 1;23(8):505-512. doi: 10.2459/JCM.0000000000001347. PMID: 35904996
Pant S, Corsini C, Baker C, Hsia TY, Pennati G, Vignon-Clementel IE
J R Soc Interface 2017 Jan;14(126) doi: 10.1098/rsif.2016.0513. PMID: 28077762Free PMC Article
Tribouilloy C, Rusinaru D, Maréchaux S, Jeu A, Ederhy S, Donal E, Réant P, Arnalsteen E, Boulanger J, Ennezat PV, Garban T, Jobic Y
Circulation 2012 Dec 11;126(24):2852-8. Epub 2012 Nov 9 doi: 10.1161/CIRCULATIONAHA.112.111260. PMID: 23143159
Zanettini R, Antonini A, Gatto G, Gentile R, Tesei S, Pezzoli G
Cardiovasc Ther 2011 Dec;29(6):404-10. Epub 2010 Jun 11 doi: 10.1111/j.1755-5922.2010.00169.x. PMID: 20553285
Ko GT, Chan HC, Chow CC
Hong Kong Med J 2003 Aug;9(4):243-6. PMID: 12904610

Clinical prediction guides

Nagorska A, Zaucker A, Lambert F, Inman A, Toral-Perez S, Gorodkin J, Wan Y, Smutny M, Sampath K
Development 2023 Dec 1;150(23) Epub 2023 Nov 30 doi: 10.1242/dev.201657. PMID: 38032088Free PMC Article
He YS, Yang M, Liu G, Ji J, Qian SY
Pediatr Pulmonol 2023 Jul;58(7):2017-2024. Epub 2023 Apr 26 doi: 10.1002/ppul.26426. PMID: 37098833
Ennezat PV, Bruneval P, Czitrom D, Gueffet JP, Piriou N, Trochu JN, Patra O, Blanchard-Lemoine B, du Fretay XH, Nazeyrollas P, Assoun B, Jobic Y, Brochet E, Bogino E, Roudaut R, Augier C, Greffe L, Petit-Eisenmann H, Dambrin C, Chavanon O, Guillou L, Grisoli D, Morera P, Banfi C, Remadi JP, Fabre O, Vincentelli A, Lantuejoul S, Ikoli JF, Copin MC, Malergue MC, Maréchaux S, Tribouilloy C
Int J Cardiol 2016 Oct 1;220:429-34. Epub 2016 Jun 23 doi: 10.1016/j.ijcard.2016.06.112. PMID: 27390966
Nielsen HH, Egeblad H, Andersen HR, Thuesen L, Poulsen SH, Klaaborg KE, Jakobsen CJ, Hjortdal VE
Scand Cardiovasc J Suppl 2013 Feb;47(1):36-41. Epub 2012 Oct 15 doi: 10.3109/14017431.2012.731519. PMID: 22989057
Corvol JC, Anzouan-Kacou JB, Fauveau E, Bonnet AM, Lebrun-Vignes B, Girault C, Agid Y, Lechat P, Isnard R, Lacomblez L
Arch Neurol 2007 Dec;64(12):1721-6. doi: 10.1001/archneur.64.12.1721. PMID: 18071034

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