"Osteocalcin" - MeSH

Select item 680156751.

Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.

Year introduced: 1990

Select item 674984732.

X11L protein, Drosophila [Supplementary Concept]

recognizes & regulates osteocalcin promoter

Date introduced: July 29, 2005

Select item 674549793.

MC2 protein, mouse [Supplementary Concept]

inversely regulated to osteocalcin in differentiating osteoblast-like cells; GenBank AJ319753; do not confuse with MC2, melanocortin receptor

Date introduced: May 23, 2002

Select item 670727014.

nuclear accessory protein, monkey [Supplementary Concept]

first isolated from monkey kidney cells; required for interaction of vitamin D receptor with vitamin D-responsive element derived from osteocalcin promotor

Date introduced: March 9, 1992

Select item 670294905.

nephrocalcin [Supplementary Concept]

a strongly acidic glycoprotein present in normal urine, which inhibits calcium oxalate crystal growth and has been isolated from urinary stone matrix

Date introduced: May 28, 1981

Select item 20277976.

BGLAP protein, human [Supplementary Concept]

RefSeq NM_199173

Date introduced: November 14, 2018

Select item 20090577.

Bonolive [Supplementary Concept]

affects serum osteocalcin levels and may stabilize lumbar spine bone mineral density