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Knockdown of GRP78 slightly prevents DOX-induced P-gp expression in OS parental cell lines and resistant sublines

(AF) OS cells and their resistant sublines were transfected transiently with siGRP78 or control siRNA for 24 hr and then treated with 1 μM DOX for 0 to 72 hr. Western blot analysis was performed with GAPDH as loading control. Data are represented as mean ± SD (n = 3).

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