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BBR increases the content of BAT and promotes the emergence of characteristics of adipose tissue browning in HF mice. The ratio of (A) inguinal white adipose tissue (I-WAT) (B) visceral white adipose tissue (V-WAT), and (C) brown adipose tissue (BAT) to total body weight, values were expressed as means± SEM (n=10), *P<0.05 and **P<0.01 compared with NCD, #P<0.05 and ##P<0.01 compared with HF. (D) Micro-CT scanning and 3D reconstruction of scapular area of mice in each group. Red areas represent interscapular BAT, Green areas represent interscapular WAT. (E) The core temperatures and (F) AUC of core temperature levels under cool exposure test were recorded every 30 min at 4°C for 2 h. Values were expressed as means± SEM (n=10), *P<0.05 and **P<0.01 compared with NCD, #P<0.05 and ##P<0.01 compared with HF.

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