Volume 108(5); 2011 Feb 1

This Week in PNAS

In This Issue

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1747–1748. Published online 2011 Feb 1. doi: 10.1073/iti0511108

PMCID:: PMC3033276

Article PDF–305K

Letters

Monoclonal tumor origin is an underlying misconception of the RESIC approach

Barbara L. Parsons

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): E15. Published online 2011 Jan 14. doi: 10.1073/pnas.1017998108

PMCID:: PMC3033296

Article PDF–431K

Reply to Parsons: Many tumor types follow the monoclonal model of tumor initiation

Yu-Kang Cheng, Rameen Beroukhim, Ross L. Levine, Ingo K. Mellinghoff, Franziska Michor

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): E16. Published online 2011 Jan 14. doi: 10.1073/pnas.1018584108

PMCID:: PMC3033310

Article PDF–433K

Commentaries

Urm1 couples sulfur transfer to ubiquitin-like protein function in oxidative stress

Matthew D. Petroski, Guy S. Salvesen, Dieter A. Wolf

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1749–1750. Published online 2011 Jan 18. doi: 10.1073/pnas.1019043108

PMCID:: PMC3033263

Article PDF–537K

Local balancing influences global structure in social networks

Aravind Srinivasan

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1751–1752. Published online 2011 Jan 20. doi: 10.1073/pnas.1018901108

PMCID:: PMC3033311

Article PDF–496K

Recalibrating Polynesian prehistory

John Edward Terrell

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1753–1754. Published online 2011 Jan 18. doi: 10.1073/pnas.1018804108

PMCID:: PMC3033261

Article PDF–576K

Physical Sciences

Applied Mathematics

Continuous-time model of structural balance

Seth A. Marvel, Jon Kleinberg, Robert D. Kleinberg, Steven H. Strogatz

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1771–1776. Published online 2011 Jan 3. doi: 10.1073/pnas.1013213108

PMCID:: PMC3033300

Abstract Article PDF–1.8M

Applied Physical Sciences

Noncontact estimation of intercellular breaking force using a femtosecond laser impulse quantified by atomic force microscopy

Yoichiroh Hosokawa, Man Hagiyama, Takanori Iino, Yoshinori Murakami, Akihiko Ito

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1777–1782. Published online 2011 Jan 18. doi: 10.1073/pnas.1006847108

PMCID:: PMC3033285

Abstract Article PDF–1.2M

Dynamically tunable hemispherical electronic eye camera system with adjustable zoom capability

Inhwa Jung, Jianliang Xiao, Viktor Malyarchuk, Chaofeng Lu, Ming Li, Zhuangjian Liu, Jongseung Yoon, Yonggang Huang, John A. Rogers

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1788–1793. Published online 2011 Jan 18. doi: 10.1073/pnas.1015440108

PMCID:: PMC3033289

Abstract Article PDF–2.2M

Chemistry

Populations of the three major backbone conformations in 19 amino acid dipeptides

Joze Grdadolnik, Vlasta Mohacek-Grosev, Robert L. Baldwin, Franc Avbelj

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1794–1798. Published online 2011 Jan 4. doi: 10.1073/pnas.1017317108

PMCID:: PMC3033284

Abstract Article PDF–402K

Chemical basis of the synergism and antagonism in microbial communities in the nests of leaf-cutting ants

Ilka Schoenian, Michael Spiteller, Manoj Ghaste, Rainer Wirth, Hubert Herz, Dieter Spiteller

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1955–1960. Published online 2011 Jan 18. doi: 10.1073/pnas.1008441108

PMCID:: PMC3033269

Abstract Article PDF–502K

Engineering

Scaling rules for diffusive drug delivery in tumor and normal tissues

James W. Baish, Triantafyllos Stylianopoulos, Ryan M. Lanning, Walid S. Kamoun, Dai Fukumura, Lance L. Munn, Rakesh K. Jain

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1799–1803. Published online 2011 Jan 11. doi: 10.1073/pnas.1018154108

PMCID:: PMC3033252

Abstract Article PDF–1.6M

Physics

From polariton condensates to highly photonic quantum degenerate states of bosonic matter

Marc Aßmann, Jean-Sebastian Tempel, Franziska Veit, Manfred Bayer, Arash Rahimi-Iman, Andreas Löffler, Sven Höfling, Stephan Reitzenstein, Lukas Worschech, Alfred Forchel

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1804–1809. Published online 2011 Jan 18. doi: 10.1073/pnas.1009847108

PMCID:: PMC3033249

Abstract Article PDF–1.3M

Colloidal quasicrystals with 12-fold and 18-fold diffraction symmetry

Steffen Fischer, Alexander Exner, Kathrin Zielske, Jan Perlich, Sofia Deloudi, Walter Steurer, Peter Lindner, Stephan Förster

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1810–1814. Published online 2011 Jan 11. doi: 10.1073/pnas.1008695108

PMCID:: PMC3033264

Abstract Article PDF–2.2M

Social Sciences

Anthropology

High-precision radiocarbon dating shows recent and rapid initial human colonization of East Polynesia

Janet M. Wilmshurst, Terry L. Hunt, Carl P. Lipo, Atholl J. Anderson

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1815–1820. Published online 2010 Dec 27. doi: 10.1073/pnas.1015876108

PMCID:: PMC3033267

Abstract Article PDF–881K

Economic Science

Being surveyed can change later behavior and related parameter estimates

Alix Peterson Zwane, Jonathan Zinman, Eric Van Dusen, William Pariente, Clair Null, Edward Miguel, Michael Kremer, Dean S. Karlan, Richard Hornbeck, Xavier Giné, Esther Duflo, Florencia Devoto, Bruno Crepon, Abhijit Banerjee

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1821–1826. Published online 2011 Jan 18. doi: 10.1073/pnas.1000776108

PMCID:: PMC3033258

Abstract Article PDF–122K

Social Science

James H. Fowler, Jaime E. Settle, Nicholas A. Christakis

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1993–1997. Published online 2011 Jan 18. doi: 10.1073/pnas.1011687108

PMCID:: PMC3033315

Abstract Article PDF–265K

Biological Sciences

Applied Biological Sciences

Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair

Tamar Harel-Adar, Tamar Ben Mordechai, Yoram Amsalem, Micha S. Feinberg, Jonathan Leor, Smadar Cohen

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1827–1832. Published online 2011 Jan 18. doi: 10.1073/pnas.1015623108

PMCID:: PMC3033268

Abstract Article PDF–1.0M

Biochemistry

Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca²⁺-ATPase in the absence of Ca²⁺

Chikashi Toyoshima, Shin-Ichiro Yonekura, Junko Tsueda, Shiho Iwasawa

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1833–1838. Published online 2011 Jan 14. doi: 10.1073/pnas.1017659108

PMCID:: PMC3033254

Abstract Article PDF–2.7M

Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome

Jianyu Zhu, Andrei Korostelev, David A. Costantino, John P. Donohue, Harry F. Noller, Jeffrey S. Kieft

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1839–1844. Published online 2011 Jan 18. doi: 10.1073/pnas.1018582108

PMCID:: PMC3033271

Abstract Article PDF–1.4M

Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex

Kouta Mayanagi, Shinichi Kiyonari, Hirokazu Nishida, Mihoko Saito, Daisuke Kohda, Yoshizumi Ishino, Tsuyoshi Shirai, Kosuke Morikawa

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1845–1849. Published online 2011 Jan 18. doi: 10.1073/pnas.1010933108

PMCID:: PMC3033280

Abstract Article PDF–1.9M

Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

Shanta Dhar, Nagesh Kolishetti, Stephen J. Lippard, Omid C. Farokhzad

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1850–1855. Published online 2011 Jan 13. doi: 10.1073/pnas.1011379108

PMCID:: PMC3033286

Abstract Article PDF–1.2M

Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog

Theodoros Goulas, Joan L. Arolas, F. Xavier Gomis-Rüth

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1856–1861. Published online 2011 Jan 13. doi: 10.1073/pnas.1012173108

PMCID:: PMC3033309

Abstract Article PDF–1.5M

Replication infidelity via a mismatch with Watson–Crick geometry

Katarzyna Bebenek, Lars C. Pedersen, Thomas A. Kunkel

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1862–1867. Published online 2011 Jan 13. doi: 10.1073/pnas.1012825108

PMCID:: PMC3033279

Abstract Article PDF–1.3M

Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling

Laura D. Jennings-Antipov, Likai Song, R. John Collier

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1868–1873. Published online 2011 Jan 24. doi: 10.1073/pnas.1018965108

PMCID:: PMC3033316

Abstract Article PDF–798K

Biophysics and Computational Biology

Reconciliation of opposing views on membrane–sugar interactions

Heidi D. Andersen, Chunhua Wang, Lise Arleth, Günther H. Peters, Peter Westh

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1874–1878. Published online 2011 Jan 18. doi: 10.1073/pnas.1012516108

PMCID:: PMC3033295

Abstract Article PDF–479K

Optimal pulse design in quantum control: A unified computational method

Jr-Shin Li, Justin Ruths, Tsyr-Yan Yu, Haribabu Arthanari, Gerhard Wagner

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1879–1884. Published online 2011 Jan 18. doi: 10.1073/pnas.1009797108

PMCID:: PMC3033291

Abstract Article PDF–635K

Tension-dependent structural deformation alters single-molecule transition kinetics

B. Sudhanshu, S. Mihardja, E. F. Koslover, S. Mehraeen, C. Bustamante, A. J. Spakowitz

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1885–1890. Published online 2011 Jan 18. doi: 10.1073/pnas.1010047108

PMCID:: PMC3033304

Abstract Article PDF–1.2M

Structural kinetics of myosin by transient time-resolved FRET

Yuri E. Nesmelov, Roman V. Agafonov, Igor V. Negrashov, Sarah E. Blakely, Margaret A. Titus, David D. Thomas

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1891–1896. Published online 2011 Jan 18. doi: 10.1073/pnas.1012320108

PMCID:: PMC3033248

Abstract Article PDF–806K

Cell Biology

Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier

Annemarthe G. Van der Veen, Kenji Schorpp, Christian Schlieker, Ludovico Buti, Jadyn R. Damon, Eric Spooner, Hidde L. Ploegh, Stefan Jentsch

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1763–1770. Published online 2011 Jan 5. doi: 10.1073/pnas.1014402108

PMCID:: PMC3033243

Abstract Article PDF–1.1M

RA-inducible gene-I induction augments STAT1 activation to inhibit leukemia cell proliferation

Lin-Jia Jiang, Nan-Nan Zhang, Fei Ding, Xian-Yang Li, Lei Chen, Hong-Xin Zhang, Wu Zhang, Sai-Juan Chen, Zhu-Gang Wang, Jun-Min Li, Zhu Chen, Jiang Zhu

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1897–1902. Published online 2011 Jan 11. doi: 10.1073/pnas.1019059108

PMCID:: PMC3033283

Abstract Article PDF–692K

Membrane lipidome of an epithelial cell line

Julio L. Sampaio, Mathias J. Gerl, Christian Klose, Christer S. Ejsing, Hartmut Beug, Kai Simons, Andrej Shevchenko

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1903–1907. Published online 2011 Jan 18. doi: 10.1073/pnas.1019267108

PMCID:: PMC3033259

Abstract Article PDF–623K

PDGF-BB and TGF-β1 on cross-talk between endothelial and smooth muscle cells in vascular remodeling induced by low shear stress

Ying-Xin Qi, Jun Jiang, Xiao-Hua Jiang, Xiao-Dong Wang, Su-Ying Ji, Yue Han, Ding-Kun Long, Bao-Rong Shen, Zhi-Qiang Yan, Shu Chien, Zong-Lai Jiang

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1908–1913. Published online 2011 Jan 18. doi: 10.1073/pnas.1019219108

PMCID:: PMC3033274

Abstract Article PDF–953K

Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6_R611C increases PDGF-dependent vascular smooth muscle cell proliferation

Ali R. Keramati, Rajvir Singh, Aiping Lin, Saeed Faramarzi, Zhi-jia Ye, Shrikant Mane, George Tellides, Richard P. Lifton, Arya Mani

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1914–1918. Published online 2011 Jan 18. doi: 10.1073/pnas.1019443108

PMCID:: PMC3033290

Abstract Article PDF–470K

Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16^INK4A and p14^ARF expression

Seiji Maruo, Bo Zhao, Eric Johannsen, Elliott Kieff, James Zou, Kenzo Takada

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1919–1924. Published online 2011 Jan 18. doi: 10.1073/pnas.1019599108

PMCID:: PMC3033265

Abstract Article PDF–812K

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)

Xiangyu Liu, Donglai Wang, Ying Zhao, Bo Tu, Zhixing Zheng, Lina Wang, Haiying Wang, Wei Gu, Robert G. Roeder, Wei-Guo Zhu

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1925–1930. Published online 2011 Jan 18. doi: 10.1073/pnas.1019619108

PMCID:: PMC3033317

Abstract Article PDF–662K

VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration

Olga V. Razorenova, Elizabeth C. Finger, Renata Colavitti, Sophia B. Chernikova, Alexander D. Boiko, Charles K. F. Chan, Adam Krieg, Barbara Bedogni, Edward LaGory, Irving L. Weissman, Marianne Broome-Powell, Amato J. Giaccia

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1931–1936. Published online 2011 Jan 13. doi: 10.1073/pnas.1011777108

PMCID:: PMC3033256

Abstract Article PDF–774K

Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin

Marc Fiedler, Carolina Mendoza-Topaz, Trevor J. Rutherford, Juliusz Mieszczanek, Mariann Bienz

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1937–1942. Published online 2011 Jan 18. doi: 10.1073/pnas.1017063108

PMCID:: PMC3033301

Abstract Article PDF–1.0M

Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel

Renaud Poincloux, Olivier Collin, Floria Lizárraga, Maryse Romao, Marcel Debray, Matthieu Piel, Philippe Chavrier

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1943–1948. Published online 2011 Jan 18. doi: 10.1073/pnas.1010396108

PMCID:: PMC3033302

Abstract Article PDF–1.1M

Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure

Laurent Sansregret, Charles Vadnais, Julie Livingstone, Nicholas Kwiatkowski, Arif Awan, Chantal Cadieux, Lam Leduy, Michael T. Hallett, Alain Nepveu

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1949–1954. Published online 2011 Jan 18. doi: 10.1073/pnas.1008403108

PMCID:: PMC3033318

Abstract Article PDF–915K

Ecology

Climate and population density drive changes in cod body size throughout a century on the Norwegian coast

Lauren A. Rogers, Leif C. Stige, Esben M. Olsen, Halvor Knutsen, Kung-Sik Chan, Nils Chr. Stenseth

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1961–1966. Published online 2011 Jan 18. doi: 10.1073/pnas.1010314108

PMCID:: PMC3033303

Abstract Article PDF–848K

Climate change induces demographic resistance to disease in novel coral assemblages

Laith Yakob, Peter J. Mumby

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1967–1969. Published online 2011 Jan 18. doi: 10.1073/pnas.1015443108

PMCID:: PMC3033278

Abstract Article PDF–205K

Determinants of lemming outbreaks

Rolf A. Ims, Nigel G. Yoccoz, Siw T. Killengreen

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1970–1974. Published online 2011 Jan 18. doi: 10.1073/pnas.1012714108

PMCID:: PMC3033251

Abstract Article PDF–624K

Strong evidence for terrestrial support of zooplankton in small lakes based on stable isotopes of carbon, nitrogen, and hydrogen

Jonathan J. Cole, Stephen R. Carpenter, Jim Kitchell, Michael L. Pace, Christopher T. Solomon, Brian Weidel

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1975–1980. Published online 2011 Jan 18. doi: 10.1073/pnas.1012807108

PMCID:: PMC3033307

Abstract Article PDF–652K

Environmental Sciences

Cellulose δ¹⁸O is an index of leaf-to-air vapor pressure difference (VPD) in tropical plants

Ansgar Kahmen, Dirk Sachse, Stefan K. Arndt, Kevin P. Tu, Heraldo Farrington, Peter M. Vitousek, Todd E. Dawson

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1981–1986. Published online 2011 Jan 18. doi: 10.1073/pnas.1018906108

PMCID:: PMC3033288

Abstract Article PDF–1.4M

Evolution

The noisy edge of traveling waves

Oskar Hallatschek

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1783–1787. Published online 2010 Dec 27. doi: 10.1073/pnas.1013529108

PMCID:: PMC3033244

Abstract Article PDF–422K

Outcrossing, mitotic recombination, and life-history trade-offs shape genome evolution in Saccharomyces cerevisiae

Paul M. Magwene, Ömür Kayıkçı, Joshua A. Granek, Jennifer M. Reininga, Zackary Scholl, Debra Murray

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1987–1992. Published online 2011 Jan 18. doi: 10.1073/pnas.1012544108

PMCID:: PMC3033294

Abstract Article PDF–330K

Genetics

SPK-1, an SR protein kinase, inhibits programmed cell death in Caenorhabditis elegans

Brendan D. Galvin, Daniel P. Denning, H. Robert Horvitz

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1998–2003. Published online 2011 Jan 18. doi: 10.1073/pnas.1018805108

PMCID:: PMC3033281

Abstract Article PDF–270K

Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements

Felizza Q. Gunderson, Evan C. Merkhofer, Tracy L. Johnson

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2004–2009. Published online 2011 Jan 18. doi: 10.1073/pnas.1011982108

PMCID:: PMC3033250

Abstract Article PDF–1.1M

Immunology

CD8⁺ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice

Hye-Jung Kim, Xuan Wang, Soroosh Radfar, Thomas J. Sproule, Derry C. Roopenian, Harvey Cantor

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2010–2015. Published online 2011 Jan 13. doi: 10.1073/pnas.1018974108

PMCID:: PMC3033298

Abstract Article PDF–862K

Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells

Hanjun Qin, Zunde Wang, Weiting Du, Wen-Hui Lee, Xiwei Wu, Arthur D. Riggs, Chih-Pin Liu

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2016–2021. Published online 2011 Jan 18. doi: 10.1073/pnas.1019082108

PMCID:: PMC3033262

Abstract Article PDF–1.0M

Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation

Eric J. Gapud, Yair Dorsett, Bu Yin, Elsa Callen, Andrea Bredemeyer, Grace K. Mahowald, Kazuo Q. Omi, Laura M. Walker, Jeffrey J. Bednarski, Peter J. McKinnon, Craig H. Bassing, Andre Nussenzweig, Barry P. Sleckman

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2022–2027. Published online 2011 Jan 18. doi: 10.1073/pnas.1013295108

PMCID:: PMC3033293

Abstract Article PDF–762K

Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions

Shan Zha, Wenxia Jiang, Yuko Fujiwara, Harin Patel, Peter H. Goff, James W. Brush, Richard L. Dubois, Frederick W. Alt

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2028–2033. Published online 2011 Jan 18. doi: 10.1073/pnas.1019293108

PMCID:: PMC3033273

Abstract Article PDF–743K

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

Marian L. Burr, Florencia Cano, Stanislava Svobodova, Louise H. Boyle, Jessica M. Boname, Paul J. Lehner

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2034–2039. Published online 2011 Jan 18. doi: 10.1073/pnas.1016229108

PMCID:: PMC3033308

Abstract Article PDF–982K

Neuropilin-1 attenuates autoreactivity in experimental autoimmune encephalomyelitis

Benjamin D. Solomon, Cynthia Mueller, Wook-Jin Chae, Leah M. Alabanza, Margaret S. Bynoe

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2040–2045. Published online 2011 Jan 18. doi: 10.1073/pnas.1008721108

PMCID:: PMC3033275

Abstract Article PDF–522K

LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8⁺ T cells

Leslie Summers deLuca, Dennis Ng, Yunfei Gao, Michael E. Wortzman, Tania H. Watts, Jennifer L. Gommerman

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2046–2051. Published online 2011 Jan 18. doi: 10.1073/pnas.1014188108

PMCID:: PMC3033245

Abstract Article PDF–1.2M

Low body temperature governs the decline of circulating lymphocytes during hibernation through sphingosine-1-phosphate

Hjalmar R. Bouma, Frans G. M. Kroese, Jan Willem Kok, Fatimeh Talaei, Ate S. Boerema, Annika Herwig, Oana Draghiciu, Azuwerus van Buiten, Anne H. Epema, Annie van Dam, Arjen M. Strijkstra, Robert H. Henning

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2052–2057. Published online 2011 Jan 18. doi: 10.1073/pnas.1008823108

PMCID:: PMC3033260

Abstract Article PDF–986K

Medical Sciences

High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy

Laura Gonzalez-Malerva, Jaehong Park, Lihua Zou, Yanhui Hu, Zahra Moradpour, Joseph Pearlberg, Jacqueline Sawyer, Hallam Stevens, Ed Harlow, Joshua LaBaer

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2058–2063. Published online 2011 Jan 13. doi: 10.1073/pnas.1018157108

PMCID:: PMC3033257

Abstract Article PDF–1.0M

Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart

Zhengxian Tao, Bo Chen, Xiao Tan, Yingming Zhao, Liansheng Wang, Tiebing Zhu, Kejiang Cao, Zhijian Yang, Yuet Wai Kan, Hua Su

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2064–2069. Published online 2011 Jan 18. doi: 10.1073/pnas.1018925108

PMCID:: PMC3033313

Abstract Article PDF–959K

A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy

Chih-Hong Wang, Feng Li, Sylvia Hiller, Hyung-Suk Kim, Nobuyo Maeda, Oliver Smithies, Nobuyuki Takahashi

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2070–2075. Published online 2011 Jan 18. doi: 10.1073/pnas.1018766108

Correction in:: Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8): 3453.

PMCID:: PMC3033253

Abstract Article PDF–916K

Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis

Jennifer M. Rosenbluth, Deborah J. Mays, Aixiang Jiang, Yu Shyr, Jennifer A. Pietenpol

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2076–2081. Published online 2011 Jan 18. doi: 10.1073/pnas.1011936108

PMCID:: PMC3033306

Abstract Article PDF–781K

Neonatal helper-dependent adenoviral vector gene therapy mediates correction of hemophilia A and tolerance to human factor VIII

Chuhong Hu, Racel G. Cela, Masataka Suzuki, Brendan Lee, Gerald S. Lipshutz

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2082–2087. Published online 2011 Jan 18. doi: 10.1073/pnas.1015571108

PMCID:: PMC3033287

Abstract Article PDF–582K

Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation

Anna E. Denoble, Kim M. Huffman, Thomas V. Stabler, Susan J. Kelly, Michael S. Hershfield, Gary E. McDaniel, R. Edward Coleman, Virginia B. Kraus

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2088–2093. Published online 2011 Jan 18. doi: 10.1073/pnas.1012743108

PMCID:: PMC3033282

Abstract Article PDF–619K

Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying

Sara Janssen, Jorien Laermans, Pieter-Jan Verhulst, Theo Thijs, Jan Tack, Inge Depoortere

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2094–2099. Published online 2011 Jan 18. doi: 10.1073/pnas.1011508108

PMCID:: PMC3033292

Abstract Article PDF–2.2M

Gastrin-releasing peptide blockade as a broad-spectrum anti-inflammatory therapy for asthma

Shutang Zhou, Erin N. Potts, Frank Cuttitta, W. Michael Foster, Mary E. Sunday

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2100–2105. Published online 2011 Jan 20. doi: 10.1073/pnas.1014792108

Retraction in:: Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1813.

PMCID:: PMC3033299

Abstract Article

Microbiology

Signal integration by DegS and RseB governs the σ^E-mediated envelope stress response in Escherichia coli

Rachna Chaba, Benjamin M. Alba, Monica S. Guo, Jungsan Sohn, Nidhi Ahuja, Robert T. Sauer, Carol A. Gross

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2106–2111. Published online 2011 Jan 18. doi: 10.1073/pnas.1019277108

PMCID:: PMC3033255

Abstract Article PDF–572K

Structures of sequential open states in a symmetrical opening transition of the TolC exit duct

Xue-Yuan Pei, Philip Hinchliffe, Martyn F. Symmons, Eva Koronakis, Roland Benz, Colin Hughes, Vassilis Koronakis

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2112–2117. Published online 2011 Jan 18. doi: 10.1073/pnas.1012588108

PMCID:: PMC3033246

Abstract Article PDF–1.0M

Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

Priya Luthra, Dengyun Sun, Robert H. Silverman, Biao He

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2118–2123. Published online 2011 Jan 18. doi: 10.1073/pnas.1012409108

PMCID:: PMC3033319

Abstract Article PDF–751K

An experimentally anchored map of transcriptional start sites in the model cyanobacterium Synechocystis sp. PCC6803

Jan Mitschke, Jens Georg, Ingeborg Scholz, Cynthia M. Sharma, Dennis Dienst, Jens Bantscheff, Björn Voß, Claudia Steglich, Annegret Wilde, Jörg Vogel, Wolfgang R. Hess

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2124–2129. Published online 2011 Jan 18. doi: 10.1073/pnas.1015154108

PMCID:: PMC3033270

Abstract Article PDF–841K

Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming

Margaret E. McLaughlin-Drubin, Christopher P. Crum, Karl Münger

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2130–2135. Published online 2011 Jan 18. doi: 10.1073/pnas.1009933108

PMCID:: PMC3033314

Abstract Article PDF–496K

Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria

Soumita Das, Katherine A. Owen, Kim T. Ly, Daeho Park, Steven G. Black, Jeffrey M. Wilson, Costi D. Sifri, Kodi S. Ravichandran, Peter B. Ernst, James E. Casanova

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2136–2141. Published online 2011 Jan 18. doi: 10.1073/pnas.1014775108

PMCID:: PMC3033312

Abstract Article PDF–680K

Neuroscience

Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3ε haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration

Paymaan Jafar-Nejad, Christopher S. Ward, Ronald Richman, Harry T. Orr, Huda Y. Zoghbi

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2142–2147. Published online 2011 Jan 18. doi: 10.1073/pnas.1018748108

PMCID:: PMC3033247

Abstract Article PDF–742K

Roller Coaster Scanning reveals spontaneous triggering of dendritic spikes in CA1 interneurons

Gergely Katona, Attila Kaszás, Gergely F. Turi, Norbert Hájos, Gábor Tamás, E. Sylvester Vizi, Balázs Rózsa

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2148–2153. Published online 2011 Jan 11. doi: 10.1073/pnas.1009270108

PMCID:: PMC3033272

Abstract Article PDF–1.1M

Plant Biology

Regulation of imprinted gene expression in Arabidopsis endosperm

Tzung-Fu Hsieh, Juhyun Shin, Rie Uzawa, Pedro Silva, Stephanie Cohen, Matthew J. Bauer, Meryl Hashimoto, Ryan C. Kirkbride, John J. Harada, Daniel Zilberman, Robert L. Fischer

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 1755–1762. Published online 2011 Jan 21. doi: 10.1073/pnas.1019273108

PMCID:: PMC3033266

Abstract Article PDF–1.0M

ORGAN BOUNDARY1 defines a gene expressed at the junction between the shoot apical meristem and lateral organs

Euna Cho, Patricia C. Zambryski

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2154–2159. Published online 2011 Jan 18. doi: 10.1073/pnas.1018542108

PMCID:: PMC3033305

Abstract Article PDF–1019K

SCARECROW-LIKE 3 promotes gibberellin signaling by antagonizing master growth repressor DELLA in Arabidopsis

Zhong-Lin Zhang, Mikihiro Ogawa, Christine M. Fleet, Rodolfo Zentella, Jianhong Hu, Jung-Ok Heo, Jun Lim, Yuji Kamiya, Shinjiro Yamaguchi, Tai-ping Sun

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2160–2165. Published online 2011 Jan 18. doi: 10.1073/pnas.1012232108

PMCID:: PMC3033277

Abstract Article PDF–884K

Funneling of gibberellin signaling by the GRAS transcription regulator SCARECROW-LIKE 3 in the Arabidopsis root

Jung-Ok Heo, Kwang Suk Chang, In A Kim, Mi-Hyun Lee, Shin Ae Lee, Sang-Kee Song, Myeong Min Lee, Jun Lim

Proc Natl Acad Sci U S A. 2011 Feb 1; 108(5): 2166–2171. Published online 2011 Jan 18. doi: 10.1073/pnas.1012215108

PMCID:: PMC3033297

Abstract Article PDF–1.1M

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences