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Review
. 1995 Sep;79(3):675-86.
doi: 10.1152/jappl.1995.79.3.675.

Oxidants and antioxidants in exercise

C K Sen  1
Affiliations
Review

Oxidants and antioxidants in exercise

C K Sen. J Appl Physiol (1985). 1995 Sep.

Abstract

There is consistent evidence from human and animal studies that strenuous physical exercise may induce a state wherein the antioxidant defenses of several tissues are overwhelmed by excess reactive oxygen. A wide variety of physiological and dietary antioxidants act in concert to evade such a stress. Submaximal long-duration exercise training may augment the physiological antioxidant defenses in several tissues; however, this enhanced protection may not be sufficient to completely protect highly fit individuals from exhaustive exercise-induced oxidative stress. Regular physical activity in association with dietary habits that ensure adequate supply of a combination of appropriate antioxidants may be expected to yield desirable results. The significance of this area of research, current state of information, and possibilities of further investigation are briefly reviewed.

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