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Synlett 2024; 35(11): 1301-1305
DOI: 10.1055/a-2214-5397
cluster
Japan/Netherlands Gratama Workshop

Synthesis of an Alternating Polycation with the Dense 1,2,3-Triazole Backbone

Tomoki Omae
a   Department of Macromolecular Science, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
,
Masaki Nakahata
a   Department of Macromolecular Science, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
,
Yuri Kamon
b   Administration Department, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
,
Akihito Hashidzume  ∗
a   Department of Macromolecular Science, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
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Abstract

Polycations are an important class of water-soluble polymers because they form polyion complexes with DNA. Thus, the synthesis of polycations with controlled monomer sequences will be of increasing importance for the formation of well-defined polyion complexes. In this study, cationic homopolymer and alternating copolymer with the dense triazole backbone were synthesized by copper(I)-catalyzed azide–alkyne cycloaddition polymerization. The polycations obtained were characterized by potentiometric and turbidimetric titrations, and by complex formation with poly(acrylic acid).

Key words

alternating copolymers - polycations - dense triazole backbone - copper(I)-catalyzed azide–alkyne cycloaddition - heterodimers

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/a-2214-5397.
  • Supporting Information


Publikationsverlauf

Eingereicht: 26. Oktober 2023

Angenommen nach Revision: 20. November 2023

Accepted Manuscript online:
20. November 2023

Artikel online veröffentlicht:
08. Januar 2024

© 2023. Thieme. All rights reserved

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