Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan;30(1):24-9.
doi: 10.1038/jhh.2015.41. Epub 2015 May 14.

Arterial stiffness in periodontitis patients and controls. A case–control and pilot intervention study

W Houcken  1 , W J Teeuw  1 , S Bizzarro  1 , E Alvarez Rodriguez  1 , T A Mulders  2 , B-Jh van den Born  2 , B G Loos  1
Affiliations

Arterial stiffness in periodontitis patients and controls. A case–control and pilot intervention study

W Houcken et al. J Hum Hypertens. 2016 Jan.

Abstract

Increased arterial stiffness (AS) is an important indicator for atherosclerotic cardiovascular disease (ACVD). Epidemiologically, periodontitis and ACVD are associated. Therefore, we aimed to investigate AS in periodontitis patients and controls. In addition, we explored the effect of periodontal therapy on AS in a sub-group of cases. Pulse-wave velocity (PWV), a non-invasive chair-side function test for AS, was measured in periodontitis patients (n=57; mean age 46.6 years) and compared with a reference group (n=48; mean age 45.5 years). In addition, 45 cases (mean age 46.9 years) were 6 months followed after periodontal treatment, to explore a possible effect on arterial function. Periodontitis patients showed a significantly increased PWV compared with the reference group (8.01±0.20 vs. 7.36±0.22 m s(-1) respectively; P=0.029) and this remained significant after adjustments for ACVD risk factors (P=0.019). After periodontal therapy, no significant reduction in PWV was seen (8.00±1.8 to 7.82±1.6 m s(-1); P=0.13), but systolic blood pressure (SBP) was significantly reduced (119.8±14.6 to 116.9±15.1 mm Hg; P=0.040). It can be concluded that periodontitis is associated with increased AS. This confirms with a new parameter the association of periodontitis with ACVD. Although periodontal treatment did not lower AS significantly, a modest reduction of SBP after 6 months was observed.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Circulation. 2010 Dec 21;122(25):e584-636 - PubMed
    1. Hypertension. 2014 Oct;64(4):702-8 - PubMed
    1. Eur J Cardiovasc Prev Rehabil. 2007 Sep;14 Suppl 2:S1-113 - PubMed
    1. Lancet. 2005 Nov 19;366(9499):1809-20 - PubMed
    1. Int J Cardiol. 2014 May 1;173(2):190-6 - PubMed

Publication types

-