Case Reports
doi: 10.1067/mob.2001.113127.
Influence of maternal and fetal glucokinase mutations in gestational diabetes
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- PMID: 11483936
- DOI: 10.1067/mob.2001.113127
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Case Reports
Influence of maternal and fetal glucokinase mutations in gestational diabetes
Am J Obstet Gynecol.
2001 Jul.
Abstract
We report 2 insulin-treated pregnancies in a mother with hyperglycemia resulting from a glucokinase gene mutation. The inheritance of a glucokinase mutation in 1 child reduced his intrauterine growth (birth weight less than first percentile) by reducing fetal insulin secretion. We discuss the implications for obstetric management of patients with glucokinase mutations.
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