doi: 10.1016/j.phytochem.2008.05.020.
Epub 2008 Jul 21.
Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp. KORDI-3973
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- PMID: 18649901
- DOI: 10.1016/j.phytochem.2008.05.020
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Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp. KORDI-3973
Phytochemistry.
2008 Sep.
Abstract
Streptopyrrolidine, a benzyl pyrrolidine derivative, was isolated as an angiogenesis inhibitor from the fermentation broth of a marine Streptomyces sp. isolated from the deep sea sediment. Its structure was elucidated by extensive 2D NMR and mass spectroscopic analyses. Streptopyrrolidine exhibited significant anti-angiogenesis activity.
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