Green tea influences intestinal assimilation of lipids in humans: a pilot study
- PMID: 25683932
Green tea influences intestinal assimilation of lipids in humans: a pilot study
Abstract
Objective: Many data show that green tea (GT) consumption has a beneficial effect on human health, including antiinflammatory, antibacterial and anticarcinogenic activities. However, there are no data on the effect of long-term GT intake on lipid assimilation not related to luminal processes. Therefore, in the present study, we aimed to assess the impact of a three-month diet enriched in green tea extract (GTE) on lipid digestion and absorption in obese humans with metabolic syndrome.
Patients and methods: Eight obese subjects aged 56-65 years, for three months, consumed a daily portion of GTE enriched bread. 13C-labelled mixed triglyceride breath test (13C MTG-BT) was performed twice; once before and once after three months of GTE consumption. Cumulative percentage dose recovery (CPDR) was assumed to reflect digestion and absorption of lipids.
Results: Energy and macronutrient intake was stable within the period study. No significant changes in basic anthropological parameters (body weight, BMI, WC, WHR), body fat content (expressed as absolute and relative values), as well as of energy expenditure in the course of the study were observed. Significant decrease in lipid digestion and absorption as assessed using the 13C MTG-BT was observed. CPDR was lower after GTE intake (median <1st-3rd quartile>: 20.8% <14.9-25.6> vs. 15.5 <12.3-20.5>; p < 0.009).
Conclusions: Long-term diet containing GTE decreases lipid assimilation, but probably without involvement of luminal effects. However, further studies are needed to confirm this hypothesis and to clarify underlying mechanism.
Similar articles
-
Safety assessment of green tea based beverages and dried green tea extracts as nutritional supplements.Toxicol Lett. 2017 Aug 5;277:104-108. doi: 10.1016/j.toxlet.2017.06.008. Epub 2017 Jun 24. Toxicol Lett. 2017. PMID: 28655517 Review.
-
Long-Term Supplementation of Green Tea Extract Does Not Modify Adiposity or Bone Mineral Density in a Randomized Trial of Overweight and Obese Postmenopausal Women.J Nutr. 2016 Feb;146(2):256-64. doi: 10.3945/jn.115.219238. Epub 2015 Dec 23. J Nutr. 2016. PMID: 26701796 Free PMC article. Clinical Trial.
-
The anti-obesity effects of green tea in human intervention and basic molecular studies.Eur J Clin Nutr. 2014 Oct;68(10):1075-87. doi: 10.1038/ejcn.2014.143. Epub 2014 Jul 30. Eur J Clin Nutr. 2014. PMID: 25074392 Review.
-
Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans.Acta Biochim Pol. 2013;60(3):481-3. Epub 2013 Aug 29. Acta Biochim Pol. 2013. PMID: 23985539
-
Antilipogenic effect of green tea extract in C57BL/6J-Lep ob/ob mice.Phytother Res. 2009 Apr;23(4):467-71. doi: 10.1002/ptr.2647. Phytother Res. 2009. PMID: 19051209
Cited by
-
The efficacy of homemade tolcapone in the treatment of patients with Parkinsons disease.Exp Ther Med. 2018 Jan;15(1):127-130. doi: 10.3892/etm.2017.5377. Epub 2017 Oct 26. Exp Ther Med. 2018. PMID: 29375679 Free PMC article.
-
Antioxidants from black and green tea: from dietary modulation of oxidative stress to pharmacological mechanisms.Br J Pharmacol. 2017 Jun;174(11):1195-1208. doi: 10.1111/bph.13649. Epub 2016 Nov 12. Br J Pharmacol. 2017. PMID: 27747873 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous