Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans
- PMID: 23985539
Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans
Abstract
Background & aims: Green tea is known worldwide for its high content of polyphenolic compounds and multifactorial beneficial effects on human health. The role of green tea as an inhibitor of lipid hydrolysis is widely discussed. The aim of the study was to assess the influence of green tea extract on lipid digestion and absorption.
Methods: The study comprised 32 healthy volunteers aged 23 to 30 years with normal exocrine pancreatic function. In all subjects (13)C-labelled mixed triglyceride breath test was performed twice with and without green tea extract ingestion. Cumulative percentage dose recovery was considered to reflect digestion and absorption of lipids. Values are expressed as medians and 1st-3rd quartile distribution.
Results: In all subjects, cumulative percentage dose recovery values were normal in a placebo test (36.8% <30.1-43.3%>). These results were significantly higher (p=0.021) than those obtained in green tea extract test (28.8% <23.1-37.2%>). Results of six tests with GTE were abnormal.
Conclusions: Single dose of green tea extract taken with a test meal decreases lipid digestion and absorption in humans.
Similar articles
-
Mulberry leaf extract decreases digestion and absorption of starch in healthy subjects-A randomized, placebo-controlled, crossover study.Adv Med Sci. 2017 Sep;62(2):302-306. doi: 10.1016/j.advms.2017.03.002. Epub 2017 May 11. Adv Med Sci. 2017. PMID: 28501729 Clinical Trial.
-
[EFFECTS OF GREEN TEA ON THE NUTRITIONAL STATUS OF THE EXERCISE].Nutr Hosp. 2015 Oct 1;32(4):1417-31. doi: 10.3305/nh.2015.32.4.9306. Nutr Hosp. 2015. PMID: 26545501 Review. Spanish.
-
Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study.Sci Rep. 2015 Jul 30;5:12015. doi: 10.1038/srep12015. Sci Rep. 2015. PMID: 26226166 Free PMC article. Clinical Trial.
-
Green tea influences intestinal assimilation of lipids in humans: a pilot study.Eur Rev Med Pharmacol Sci. 2015;19(2):209-14. Eur Rev Med Pharmacol Sci. 2015. PMID: 25683932 Clinical Trial.
-
Pharmacological effects of green tea on the gastrointestinal system.Eur J Pharmacol. 2004 Oct 1;500(1-3):177-85. doi: 10.1016/j.ejphar.2004.07.023. Eur J Pharmacol. 2004. PMID: 15464031 Review.
Cited by
-
Effect of Macrotyloma uniflorum on antiobesity in rats fed with a high fat diet.Saudi J Biol Sci. 2019 Nov;26(7):1772-1778. doi: 10.1016/j.sjbs.2018.05.003. Epub 2018 May 3. Saudi J Biol Sci. 2019. PMID: 31762657 Free PMC article. No abstract available.
-
Effect of Acute Ingestion of Green Tea Extract and Lemon Juice on Oxidative Stress and Lipid Profile in Pigs Fed a High-Fat Diet.Antioxidants (Basel). 2019 Jun 23;8(6):195. doi: 10.3390/antiox8060195. Antioxidants (Basel). 2019. PMID: 31234608 Free PMC article.
-
Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial.J Tradit Complement Med. 2017 Nov 6;8(3):391-395. doi: 10.1016/j.jtcme.2017.07.005. eCollection 2018 Jul. J Tradit Complement Med. 2017. PMID: 29992110 Free PMC article.
-
Enrichment of Biscuits with Matcha Green Tea Powder: Its Impact on Consumer Acceptability and Acute Metabolic Response.Foods. 2018 Feb 1;7(2):17. doi: 10.3390/foods7020017. Foods. 2018. PMID: 29389844 Free PMC article.
-
Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity.Molecules. 2016 Sep 29;21(10):1305. doi: 10.3390/molecules21101305. Molecules. 2016. PMID: 27689985 Free PMC article. Review.