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. 1987;31(5):625-7.
doi: 10.1007/BF00606644.

Verapamil and norverapamil in plasma and breast milk during breast feeding

P Anderson, U Bondesson, I Mattiasson, B W Johansson

Verapamil and norverapamil in plasma and breast milk during breast feeding

P Anderson et al. Eur J Clin Pharmacol. 1987.

Abstract

The concentrations of verapamil and norverapamil have been measured in milk and plasma samples from a 32 year-old woman treated with verapamil 80 mg tds while breast-feeding her child. The average steady-state concentrations of verapamil and noverapamil in milk were, respectively, 60% and 16% of the concentrations in plasma. The breast-fed child received less than 0.01% of the dose of verapamil given to the mother. No verapamil or norverapamil (less than 1 ng/ml) could be detected in the plasma from the child.

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