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Editorial
. 2024 Jul;133(1):16-18.
doi: 10.1016/j.bja.2024.04.005. Epub 2024 May 16.

A new pharmacological approach for tracheal intubation?

J Robert Sneyd  1
Affiliations
Editorial

A new pharmacological approach for tracheal intubation?

J Robert Sneyd. Br J Anaesth. 2024 Jul.

Abstract

Anaesthesia induced with remimazolam and a fentanyl-series opioid can be reversed with flumazenil and naloxone. Concomitant paralysis with rocuronium can facilitate tracheal intubation whilst being reversible with sugammadex. Together, this combination might offer full reversibility of a 'routine' or a 'rapid-sequence' induction anaesthesia. Whether this is useful, or even safe, requires careful evaluation.

Keywords: flumazenil; naloxone; neuromuscular block; rapid sequence induction; remimazolam; reversal; rocuronium; sugammadex.

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