ESR2 (estrogen receptor 2) - Rat Genome Database

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Gene: ESR2 (estrogen receptor 2) Pan paniscus
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Symbol: ESR2
Name: estrogen receptor 2
RGD ID: 12031318
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); enzyme binding (ortholog); estradiol binding (ortholog); INVOLVED IN amygdala development (ortholog); androgen receptor signaling pathway (ortholog); behavioral fear response (ortholog); PARTICIPATES IN bisphenol A response pathway; estrogen signaling pathway; tamoxifen pharmacodynamics pathway; ASSOCIATED WITH adenocarcinoma (ortholog); adenoma (ortholog); Alzheimer's disease (ortholog); FOUND IN neuronal cell body (ortholog); perikaryon (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: estrogen receptor beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan1-v2NHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBINHGRI_mPanPan1Mhudiblu_PPA_v01444,807,875 - 44,919,780 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3PanPan1.11463,064,397 - 63,175,303 (-)NCBIpanpan1.1PanPan1.1panPan2PanPan1.1 Ensembl1463,064,402 - 63,131,303 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
ESR2Bonoboadenoma  ISOESR2 (Homo sapiens)9068941ratio with Esr1 and mRNA:decreased expression:thyroid gland (human)RGDPMID:11721176 and REF_RGD_ID:8694118
ESR2Bonoboalopecia no_associationISOESR2 (Homo sapiens)9068941DNA:snps:multiple (human)RGDPMID:22509838 and REF_RGD_ID:8694094
ESR2Bonoboalopecia susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps:enhancer more ...RGDPMID:22014031 and REF_RGD_ID:8694095
ESR2BonoboAlzheimer's disease  ISOEsr2 (Mus musculus)9068941mRNA:increased expression:cerebral cortexRGDPMID:15916731 and REF_RGD_ID:5508772
ESR2BonoboAlzheimer's disease  ISOESR2 (Homo sapiens)9068941protein:decreased expression:choroid plexusRGDPMID:15082146 and REF_RGD_ID:5508784
ESR2BonoboAlzheimer's disease susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps:introns:IVS3-1880C>T more ...RGDPMID:15944651 and REF_RGD_ID:8693346
ESR2BonoboAlzheimer's disease susceptibilityISOESR2 (Homo sapiens)9068941DNA:SNPs:3' utr: (rs4986938), (rs1255953) (human)RGDPMID:17132983 and REF_RGD_ID:5508768
ESR2Bonoboanxiety disorder treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24015243 more ...
ESR2Bonoboaortic valve stenosis  ISOESR2 (Homo sapiens)9068941 RGDPMID:15533858 and REF_RGD_ID:1580704
ESR2Bonoboasthma  ISOEsr2 (Rattus norvegicus)9068941mRNA:decreased expression:lung (rat)RGDPMID:18375789 and REF_RGD_ID:8694127
ESR2Bonoboatherosclerosis  ISOEsr2 (Mus musculus)9068941 RGDPMID:21697723 and REF_RGD_ID:5508792
ESR2BonoboBlast Crisis  ISOEsr2 (Mus musculus)9068941 RGDPMID:12740446 and REF_RGD_ID:734951
ESR2Bonobobrain ischemia  ISOEsr2 (Rattus norvegicus)9068941mRNA:decreased expression:cerebral cortex and ipsilateral side (rat)RGDPMID:10414967 and REF_RGD_ID:8694344
ESR2Bonobobreast cancer no_associationISOESR2 (Homo sapiens)9068941DNA:snps:multiple (human)RGDPMID:19321582 and REF_RGD_ID:8694110
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:silent mutation:exon:g.1176C>G (rs1256054) (human)RGDPMID:20604969 and REF_RGD_ID:8694116
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:repeat:intron:IVS5(CA)9-31 (human)RGDPMID:22792352 and REF_RGD_ID:8694096
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps more ...RGDPMID:16261413 and REF_RGD_ID:8694090
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:snp:promoter:g.-13950C>T (rs2987983) (human)RGDPMID:19429453 and REF_RGD_ID:8693347
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps and haplotype:multiple (human)RGDPMID:15604249 and REF_RGD_ID:8552978
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941associated with Benign Breast Disease and DNA:snp:3' utr:*5772A>G (rs8018687) (human)RGDPMID:16808847 and REF_RGD_ID:8693380
ESR2Bonobobreast cancer treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23700476 and REF_RGD_ID:7364946
ESR2Bonobobreast cancer  ISOESR2 (Homo sapiens)9068941DNA:repeat:3' utr:(CA)10-27 (human)RGDPMID:17904846 and REF_RGD_ID:8552977
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps:intron more ...RGDPMID:14633679 and REF_RGD_ID:8694103
ESR2Bonobobreast cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps:5' utr more ...RGDPMID:19739075 and REF_RGD_ID:8693382
ESR2BonoboBreast Neoplasms treatmentISOESR2 (Homo sapiens)9068941 RGDPMID:24047421 and REF_RGD_ID:8552984
ESR2BonoboBreast Neoplasms disease_progressionISOESR2 (Homo sapiens)9068941mRNA and protein:increased expression:breastRGDPMID:18234277 and REF_RGD_ID:2290017
ESR2BonoboCognitive Dysfunction susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps:introns and exon:C>T (rs1256030), A>C (rs1256065), C>G (rs1255998) (human)RGDPMID:17889406 and REF_RGD_ID:8694087
ESR2Bonobocolitis  ISOEsr2 (Rattus norvegicus)9068941mRNA:decreased expression:colonRGDPMID:21252046 and REF_RGD_ID:5508810
ESR2Bonobocolitis  ISOEsr2 (Mus musculus)9068941mRNA:decreased expression:colonRGDPMID:21252046 and REF_RGD_ID:5508810
ESR2Bonobocolon cancer  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:19141699 and REF_RGD_ID:8694174
ESR2Bonobocolorectal cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:repeat:3' utr:g.dupCA (human)RGDPMID:21884200 and REF_RGD_ID:7364791
ESR2Bonobocontact dermatitis severityISOEsr2 (Mus musculus)9068941 RGDPMID:18167605 and REF_RGD_ID:8694123
ESR2Bonobocoronary artery disease  ISOESR2 (Homo sapiens)9068941 RGDPMID:16099331 and REF_RGD_ID:1581014
ESR2BonoboCOVID-19  ISOESR2 (Homo sapiens)9068941mRNA:decreased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
ESR2BonoboCrohn's disease disease_progressionISOESR2 (Homo sapiens)9068941mRNA:decreased expression:colonRGDPMID:21252046 and REF_RGD_ID:5508810
ESR2Bonobocystitis  ISOEsr2 (Rattus norvegicus)9068941protein:decreased expression:bladderRGDPMID:16894621 and REF_RGD_ID:5508847
ESR2BonoboDeafness  ISOEsr2 (Mus musculus)9068941 RGDPMID:19293293 and REF_RGD_ID:8553051
ESR2Bonobodepressive disorder treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24128867 and REF_RGD_ID:10045672
ESR2Bonoboendometriosis  ISOEsr2 (Mus musculus)9068941 RGDPMID:15618247 and REF_RGD_ID:5509040
ESR2BonoboExperimental Arthritis  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16269464 and REF_RGD_ID:5508854
ESR2BonoboExperimental Autoimmune Encephalomyelitis  ISOEsr2 (Mus musculus)9068941 RGDPMID:21182085 more ...
ESR2BonoboExperimental Mammary Neoplasms  ISOEsr2 (Rattus norvegicus)9068941protein:increased expression:epithelial cell and nucleusRGDPMID:15637090 and REF_RGD_ID:8552983
ESR2BonoboExperimental Mammary Neoplasms treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24078029 and REF_RGD_ID:7364911
ESR2BonoboExperimental Melanoma severityISOEsr2 (Mus musculus)9068941 RGDPMID:20354658 and REF_RGD_ID:8694122
ESR2BonoboFemale Infertility  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:28520870 and REF_RGD_ID:38548924
ESR2Bonoboglomerulosclerosis susceptibilityISOEsr2 (Mus musculus)9068941protein:decreased expression:renal glomerulus (mouse)RGDPMID:12000739 and REF_RGD_ID:7364801
ESR2BonoboGraves' disease susceptibilityISOESR2 (Homo sapiens)9068941DNA:snp:intron:IVS8G>A (rs4986938) (human)RGDPMID:17941906 and REF_RGD_ID:8693348
ESR2BonoboGraves' disease no_associationISOESR2 (Homo sapiens)9068941DNA:repeatRGDPMID:11180758 and REF_RGD_ID:10045850
ESR2BonoboHand Osteoarthritis no_associationISOESR2 (Homo sapiens)9068941DNA:SNPs:introns: (rs1256034 more ...RGDPMID:19884274 and REF_RGD_ID:10045830
ESR2BonoboHashimoto Disease no_associationISOESR2 (Homo sapiens)9068941DNA:repeatRGDPMID:11180758 and REF_RGD_ID:10045850
ESR2BonoboHearing Loss  ISOEsr2 (Mus musculus)9068941 RGDPMID:18317592 and REF_RGD_ID:8553063
ESR2BonoboHemorrhagic Shock  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16859701 and REF_RGD_ID:8694176
ESR2BonoboHot Flashes treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24823389 and REF_RGD_ID:10045671
ESR2BonoboHyperalgesia  ISOEsr2 (Mus musculus)9068941 RGDPMID:19285805 and REF_RGD_ID:8553066
ESR2BonoboHyperalgesia  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17056036 and REF_RGD_ID:5508846
ESR2Bonobohypertension  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23608653 and REF_RGD_ID:7364951
ESR2Bonobohypertension  ISOEsr2 (Mus musculus)9068941 RGDPMID:11799247 and REF_RGD_ID:734949
ESR2Bonobohypertension  ISOESR2 (Homo sapiens)9068941 RGDPMID:11185739 more ...
ESR2Bonobohypospadias susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps more ...RGDPMID:17579196 and REF_RGD_ID:1626506
ESR2Bonoboin situ carcinoma  ISOESR2 (Homo sapiens)9068941protein:decreased expression:breastRGDPMID:17924141 and REF_RGD_ID:2290024
ESR2Bonoboinflammatory bowel disease  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:14500559 and REF_RGD_ID:5509042
ESR2Bonobointerstitial cystitis  ISOEsr2 (Mus musculus)9068941 RGDPMID:17522255 and REF_RGD_ID:7364800
ESR2BonoboKnee Osteoarthritis  ISOESR2 (Homo sapiens)9068941DNA:repeat:intron:c.1092+3607(CA)13-27 (human)RGDPMID:16098017 and REF_RGD_ID:10043199
ESR2BonoboLeft Ventricular Hypertrophy  ISOESR2 (Homo sapiens)9068941 RGDPMID:16280269 and REF_RGD_ID:1581013
ESR2BonoboLeft Ventricular Hypertrophy  ISOEsr2 (Mus musculus)9068941 RGDPMID:16627800 and REF_RGD_ID:1581018
ESR2BonoboLung Injury  ISOEsr2 (Rattus norvegicus)9068941associated with Shock and HemorrhagicRGDPMID:20195535 and REF_RGD_ID:4892252
ESR2Bonobomelanoma severityISOESR2 (Homo sapiens)9068941 RGDPMID:19153340 and REF_RGD_ID:8553064
ESR2Bonobomyasthenia gravis  ISOESR2 (Homo sapiens)9068941 RGDPMID:15661863 and REF_RGD_ID:5509039
ESR2Bonobomyeloid leukemia  ISOEsr2 (Mus musculus)9068941 RGDPMID:12740446 and REF_RGD_ID:734951
ESR2BonoboMyocardial Reperfusion Injury  ISOEsr2 (Mus musculus)9068941 RGDPMID:18656630 and REF_RGD_ID:5508820
ESR2Bonoboobesity  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:22230815 and REF_RGD_ID:8553199
ESR2Bonoboosteoarthritis  ISOESR2 (Homo sapiens)9068941DNA:SNP:intron: (rs1256031) (human)RGDPMID:19884274 and REF_RGD_ID:10045830
ESR2Bonoboosteoporosis  ISOEsr2 (Mus musculus)9068941 RGDPMID:21421090 and REF_RGD_ID:10045841
ESR2Bonoboosteoporosis  ISOESR2 (Homo sapiens)9068941DNA:SNP and haplotype:3'utr:*39A>G (human)RGDPMID:16530497 and REF_RGD_ID:10045825
ESR2Bonoboosteoporosis susceptibilityISOESR2 (Homo sapiens)9068941DNA:repeat:3' utr: g.dupCA (human)RGDPMID:22948905 and REF_RGD_ID:7364765
ESR2Bonoboosteoporosis susceptibilityISOESR2 (Homo sapiens)9068941DNA:SNP and haplotypes: :-1213T>C (human)RGDPMID:16777502 and REF_RGD_ID:1626507
ESR2Bonoboosteoporosis treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16955786 and REF_RGD_ID:8694129
ESR2BonoboOsteoporotic Fractures  ISOESR2 (Homo sapiens)9068941DNA:SNP: :-1213T>C (human)RGDPMID:16777502 and REF_RGD_ID:1626507
ESR2BonoboOsteoporotic Fractures  ISOESR2 (Homo sapiens)9068941DNA:SNPs more ...RGDPMID:16939403 and REF_RGD_ID:10045848
ESR2BonoboOsteoporotic Fractures  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:25085540 and REF_RGD_ID:10045675
ESR2BonoboParkinson's disease onsetISOESR2 (Homo sapiens)9068941DNA:polymorphism: :1730A>G(human) RGDPMID:15219649 and REF_RGD_ID:5508776
ESR2Bonoboperitonitis treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23063870 and REF_RGD_ID:8553243
ESR2BonoboPituitary Neoplasms  ISOESR2 (Homo sapiens)9068941mRNA:decreased expression:pituitary gland (human)RGDPMID:11081187 and REF_RGD_ID:8694115
ESR2BonoboPostmenopausal Osteoporosis susceptibilityISOESR2 (Homo sapiens)9068941DNA:SNP and haplotype:3'utr:*39A>G (human)RGDPMID:22335445 and REF_RGD_ID:10045849
ESR2BonoboPostmenopausal Osteoporosis susceptibilityISOESR2 (Homo sapiens)9068941DNA:repeat:intron:IVS5-3919(CA)18-26 (human)RGDPMID:17945165 and REF_RGD_ID:10045847
ESR2BonoboPostmenopausal Osteoporosis susceptibilityISOESR2 (Homo sapiens)9068941DNA:SNP: :-1213T>C (human)RGDPMID:16777502 and REF_RGD_ID:1626507
ESR2Bonobopre-eclampsia  ISOESR2 (Homo sapiens)9068941 RGDPMID:15894829 and REF_RGD_ID:1581016
ESR2Bonoboprimary open angle glaucoma severityISOESR2 (Homo sapiens)9068941DNA:snps:introns: IVS3 T>C more ...RGDPMID:20399928 and REF_RGD_ID:8694092
ESR2Bonoboprimary open angle glaucoma  ISOESR2 (Homo sapiens)9068941DNA:SNPs and haplotypesRGDPMID:18195227 and REF_RGD_ID:8553056
ESR2Bonoboprostate cancer susceptibilityISOESR2 (Homo sapiens)9068941DNA:snps and haplotype:multiple (human)RGDPMID:17932344 and REF_RGD_ID:8694101
ESR2Bonoboprostate carcinoma in situ treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:22025007 and REF_RGD_ID:8553211
ESR2Bonoboprostatic hypertrophy treatmentISOEsr2 (Mus musculus)9068941 RGDPMID:17068134 and REF_RGD_ID:8552985
ESR2BonoboProstatic Neoplasms disease_progressionISOESR2 (Homo sapiens)9068941mRNA:decreased expression:prostate glandRGDPMID:17908481 and REF_RGD_ID:2290023
ESR2Bonobopulmonary hypertension  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:21700911 and REF_RGD_ID:5508791
ESR2Bonoboretinal degeneration  ISOEsr2 (Mus musculus)9068941 RGDPMID:19799898 and REF_RGD_ID:8694106
ESR2Bonoborheumatoid arthritis severityISOESR2 (Homo sapiens)9068941DNA:SNP:exon:rs1256049(human)RGDPMID:21523342 and REF_RGD_ID:5508794
ESR2BonoboSepsis  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16755255 and REF_RGD_ID:5508850
ESR2BonoboSpinal Cord Injuries  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:25105782 and REF_RGD_ID:10045844
ESR2BonoboSplenomegaly  ISOEsr2 (Mus musculus)9068941 RGDPMID:12740446 and REF_RGD_ID:734951
ESR2BonoboStroke treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24406718 and REF_RGD_ID:10045677
ESR2Bonobosystemic lupus erythematosus  ISOESR2 (Homo sapiens)9068941mRNA:increased expression: :RGDPMID:20627037 and REF_RGD_ID:5508813
ESR2Bonobosystemic lupus erythematosus susceptibilityISOESR2 (Homo sapiens)9068941DNA:SNP: :rs4986938 (human) RGDPMID:20961965 and REF_RGD_ID:5508738
ESR2Bonobosystemic lupus erythematosus  ISOEsr2 (Mus musculus)9068941 RGDPMID:17336162 and REF_RGD_ID:5508844
ESR2Bonobosystemic lupus erythematosus susceptibilityISOESR2 (Homo sapiens)9068941DNA:repeats:intron:RGDPMID:20305046 and REF_RGD_ID:5508817
ESR2Bonobosystemic lupus erythematosus  ISOESR2 (Homo sapiens)9068941mRNA:decreased expression:leukocyte and mononuclearRGDPMID:17874259 and REF_RGD_ID:5508843
ESR2Bonobosystemic scleroderma no_associationISOESR2 (Homo sapiens)9068941DNA:SNP:exon:RGDPMID:19032828 and REF_RGD_ID:8553058
ESR2Bonobotransient cerebral ischemia  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23593292 and REF_RGD_ID:7364962
ESR2Bonoboulcerative colitis  ISOESR2 (Homo sapiens)9068941mRNA:decreased expression:colonRGDPMID:21252046 and REF_RGD_ID:5508810
ESR2Bonobourinary bladder cancer severityISOESR2 (Homo sapiens)9068941protein:increased expression:urinary bladder urothelium (human)RGDPMID:23612777 and REF_RGD_ID:7364758
ESR2BonoboUrination Disorders treatmentISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24259512 and REF_RGD_ID:10045674
ESR2BonoboVaricose Ulcer  ISOESR2 (Homo sapiens)9068941DNA:polymorphism:intron:(CA) dinucleotide repeat (human)RGDPMID:16153823 and REF_RGD_ID:1626508
ESR2BonoboVaricose Ulcer  ISOESR2 (Homo sapiens)9068941DNA:SNPs:promoter and exonRGDPMID:18070128 and REF_RGD_ID:8553061
ESR2BonoboVulvar Lichen Sclerosus  ISOESR2 (Homo sapiens)9068941 RGDPMID:18076706 and REF_RGD_ID:2293866

Imported Disease Annotations - ClinVar

Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
ESR2Bonoboovarian dysgenesis 8  ISOESR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Ovarian dysgenesis 8ClinVarPMID:30113650

Imported Disease Annotations - CTD

Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)ESR2Bonoboadenocarcinoma  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17639508ESR2BonoboAnimal Mammary Neoplasms  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15637090ESR2Bonoboatrial fibrillation  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:30061737ESR2BonoboBreast Neoplasms  ISOESR2 (Homo sapiens)9068941CTD more ...CTDPMID:17132221 more ...ESR2Bonobocarcinoma  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15637090ESR2BonoboCardiac Arrhythmias  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22166976ESR2BonoboCocaine-Related Disorders  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17133264ESR2BonoboColorectal Neoplasms  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15954165ESR2Bonobocoronary artery disease  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20559769ESR2BonoboCoronary Disease  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17367797ESR2BonoboEndometrial Neoplasms  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25437045ESR2Bonoboendometriosis  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17625110ESR2BonoboExperimental Mammary Neoplasms  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15637090ESR2BonoboFemale Infertility  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23710174ESR2BonoboLithiasis  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21670126ESR2Bonobomalignant astrocytoma  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:24680642ESR2Bonobomedulloblastoma  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: therapeuticCTDPMID:21351254ESR2BonoboNeoplastic Cell Transformation  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: therapeuticCTDPMID:22398780ESR2Bonoboprostate carcinoma in situ  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16220300ESR2BonoboProstatic Neoplasms  ISOESR2 (Homo sapiens)9068941CTD more ...CTDPMID:15046698 more ...ESR2Bonobotransitional cell carcinoma  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16700038ESR2Bonobourinary bladder cancer  ISOESR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16700038

Imported Disease Annotations - OMIM

Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)ESR2Bonoboovarian dysgenesis 8  ISOESR2 (Homo sapiens)7240710 OMIM 

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process

  
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)ESR2Bonoboamygdala development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:22791648 and REF_RGD_ID:8694158ESR2Bonoboandrogen receptor signaling pathway acts_upstream_ofISOMGI:21522179068941 PMID:12370428MGIPMID:12370428ESR2Bonobobehavioral fear response  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15514081 and REF_RGD_ID:1582265ESR2Bonobobrain development acts_upstream_of_or_withinISOMGI:21522179068941 PMID:12515851MGIPMID:12515851ESR2Bonobocell population proliferation acts_upstream_ofISOMGI:880399068941 PMID:18464259MGIPMID:18464259ESR2Bonobocellular response to estradiol stimulus  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonobocellular response to estradiol stimulus involved_inIEAInterPro:IPR028355150520179 InterProGO_REF:0000002ESR2Bonobocellular response to estrogen stimulus involved_inIEAPANTHER:PTN000639432150520179 TreeGrafterGO_REF:0000118ESR2Bonobocellular response to lipopolysaccharide  ISOEsr2 (Rattus norvegicus)9068941negative regulation of cell deathRGDPMID:21127968 and REF_RGD_ID:5508811ESR2Bonobocellular response to magnetism  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23469792 and REF_RGD_ID:7365032ESR2Bonobocellular response to organic cyclic compound  ISOEsr2 (Rattus norvegicus)9068941naringinRGDPMID:23596885 and REF_RGD_ID:7364961ESR2Bonobocellular response to xenobiotic stimulus  ISOEsr2 (Rattus norvegicus)9068941tamoxifenRGDPMID:19279558 and REF_RGD_ID:7364795ESR2Bonobocerebellum development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16542644 and REF_RGD_ID:1601098ESR2Bonoboepithelial cell maturation involved in prostate gland development acts_upstream_of_or_withinISOMGI:21522179068941 PMID:15187231MGIPMID:15187231ESR2Bonoboepithelial cell proliferation acts_upstream_ofISOMGI:21522179068941 PMID:12370428 and PMID:15187231MGIPMID:12370428 and PMID:15187231ESR2Bonoboestrogen receptor signaling pathway involved_inIEAPANTHER:PTN000639432150520179 TreeGrafterGO_REF:0000118ESR2Bonoboestrogen receptor signaling pathway acts_upstream_of_or_withinISOMGI:21522179068941 PMID:12370428MGIPMID:12370428ESR2Bonoboestrogen receptor signaling pathway involved_inIEAInterPro:IPR028355150520179 InterProGO_REF:0000002ESR2Bonoboestrous cycle  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:11854469 and REF_RGD_ID:8694160ESR2Bonobofemale gonad development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:9927330 and REF_RGD_ID:8694313ESR2Bonobohormone-mediated apoptotic signaling pathway acts_upstream_of_or_withinISOMGI:21522179068941 PMID:15187231MGIPMID:15187231ESR2Bonobohypothalamus development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:12960049 and REF_RGD_ID:1582276ESR2Bonobolearning or memory  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16904920 and REF_RGD_ID:1626504ESR2Bonobomale gonad development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15944240 more ...ESR2Bonobonegative regulation of androgen receptor signaling pathway acts_upstream_of_or_withinISOMGI:21522179068941 PMID:12370428MGIPMID:12370428ESR2Bonobonegative regulation of behavior  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15514081 and REF_RGD_ID:1582265ESR2Bonobonegative regulation of cell population proliferation acts_upstream_of_or_withinISOMGI:880399068941 PMID:18464259MGIPMID:18464259ESR2Bonobonegative regulation of epithelial cell proliferation  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:12370428 and REF_RGD_ID:625746ESR2Bonobonegative regulation of epithelial cell proliferation acts_upstream_of_or_withinISOMGI:21522179068941 PMID:12370428 and PMID:15187231MGIPMID:12370428 and PMID:15187231ESR2Bonobonegative regulation of feeding behavior  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:12119576 and REF_RGD_ID:8694342ESR2Bonobonegative regulation of neuron apoptotic process  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15126114 and REF_RGD_ID:1582270ESR2Bonobonegative regulation of reactive oxygen species metabolic process  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23608653 and REF_RGD_ID:7364951ESR2Bonobonegative regulation of smooth muscle cell proliferation  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:22099601 and REF_RGD_ID:8553200ESR2Bonobonegative regulation of transcription by RNA polymerase II  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:9600083 and REF_RGD_ID:728646ESR2Bonobonegative regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonoboneuron migration acts_upstream_of_or_withinISOMGI:21522179068941 PMID:12515851MGIPMID:12515851ESR2Bonobonuclear receptor-mediated steroid hormone signaling pathway  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonoboovarian follicle development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17971845 and REF_RGD_ID:2289161ESR2Bonoboovarian follicle development acts_upstream_of_or_withinISOMGI:23867619068941 PMID:10976058MGIPMID:10976058ESR2Bonoboovarian follicle development acts_upstream_of_or_withinISOMGI:21522179068941 PMID:9861029MGIPMID:9861029ESR2Bonobopositive regulation of apoptotic process  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:22025007 and REF_RGD_ID:8553211ESR2Bonobopositive regulation of DNA-templated transcription  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15564578 and REF_RGD_ID:1582269ESR2Bonobopositive regulation of DNA-templated transcription involved_inIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonobopositive regulation of epidermal growth factor receptor signaling pathway  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonobopositive regulation of ERK1 and ERK2 cascade  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17928626 more ...ESR2Bonobopositive regulation of transcription by RNA polymerase II  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15564578 and REF_RGD_ID:1582269ESR2Bonobopositive regulation of transcription by RNA polymerase II involved_inISOESR2 (Homo sapiens)9068941 PMID:24033289CAFAPMID:24033289ESR2Bonobopositive regulation of transcription by RNA polymerase II involved_inISOEsr2 (Rattus norvegicus)9068941PMID:12047722NTNU_SBPMID:12047722 and REF_RGD_ID:8661629ESR2Bonoboprostate gland development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:9492016 and REF_RGD_ID:8694133ESR2Bonoboprostate gland epithelium morphogenesis acts_upstream_of_or_withinISOMGI:21522179068941 PMID:12370428 and PMID:15187231MGIPMID:12370428 and PMID:15187231ESR2Bonoboregulation of cell population proliferation acts_upstream_of_or_withinISOMGI:18579369068941 PMID:9697695MGIPMID:9697695ESR2Bonoboregulation of DNA-templated transcription involved_inIEAInterPro:IPR001628 more ...150520179 InterProGO_REF:0000002ESR2Bonoboregulation of transcription by RNA polymerase II involved_inIEAPANTHER:PTN000639432150520179 TreeGrafterGO_REF:0000118ESR2Bonoboresponse to activity  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:18516675 and REF_RGD_ID:8694113ESR2Bonoboresponse to bisphenol A  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:22957036 and REF_RGD_ID:9743854ESR2Bonoboresponse to dexamethasone  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15087431 and REF_RGD_ID:8694155ESR2Bonoboresponse to estradiol  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:19948032 and REF_RGD_ID:5508718ESR2Bonoboresponse to estrogen  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15667451 and REF_RGD_ID:8694128ESR2Bonoboresponse to ethanol  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23591044 and REF_RGD_ID:7364963ESR2Bonoboresponse to genistein  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:19230619 and REF_RGD_ID:7364797ESR2Bonoboresponse to hormone  ISOEsr2 (Rattus norvegicus)9068941melatoninRGDPMID:23591044 and REF_RGD_ID:7364963ESR2Bonoboresponse to human chorionic gonadotropin  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:10342845 and REF_RGD_ID:8694156ESR2Bonoboresponse to insecticide  ISOEsr2 (Rattus norvegicus)9068941dimethoateRGDPMID:23943137 and REF_RGD_ID:7364910ESR2Bonoboresponse to lipid involved_inIEAARBA:ARBA00028073150520179 UniProtGO_REF:0000117ESR2Bonoboresponse to nutrient levels  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:18596125 and REF_RGD_ID:8694126ESR2Bonoboresponse to organic cyclic compound  ISOEsr2 (Rattus norvegicus)90689414-nitrophenolRGDPMID:24070737 and REF_RGD_ID:7364802ESR2Bonoboresponse to organic cyclic compound involved_inIEAARBA:ARBA00027206150520179 UniProtGO_REF:0000117ESR2Bonoboresponse to salt  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:12764114 and REF_RGD_ID:8694168ESR2Bonoboresponse to testosterone  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16904920 more ...ESR2Bonoboresponse to xenobiotic stimulus  ISOEsr2 (Rattus norvegicus)9068941RU486RGDPMID:20686183 and REF_RGD_ID:8694171ESR2BonoboSertoli cell development  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24056172 and REF_RGD_ID:7364870ESR2BonoboSertoli cell proliferation  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonobouterus development acts_upstream_of_or_withinISOMGI:13524679068941 PMID:10976058MGIPMID:10976058ESR2Bonobovagina development acts_upstream_of_or_withinISOMGI:13524679068941 PMID:10976058MGIPMID:10976058ESR2Bonobovasodilation  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24440742 and REF_RGD_ID:10045880

Cellular Component

  
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)ESR2Bonobocytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044ESR2Bonobointracellular membrane-bounded organelle located_inIEAUniProtKB:Q7LCB3 more ...150520179 EnsemblGO_REF:0000107ESR2Bonobomitochondrion located_inIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonoboneuronal cell body  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:23701910 and REF_RGD_ID:7364912ESR2Bonobonucleoplasm located_inIEAUniProtKB:Q7LCB3 more ...150520179 EnsemblGO_REF:0000107ESR2Bonobonucleoplasm located_inIEAARBA:ARBA00026290150520179 UniProtGO_REF:0000117ESR2Bonobonucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043ESR2Bonobonucleus located_inIEAPANTHER:PTN000639432150520179 TreeGrafterGO_REF:0000118ESR2Bonobonucleus located_inIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonobonucleus located_inIEAInterPro:IPR024178150520179 InterProGO_REF:0000002ESR2Bonobonucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044ESR2Bonoboperikaryon  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:16122717 and REF_RGD_ID:1582179ESR2Bonoboperinuclear region of cytoplasm  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonoboprotein-DNA complex  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:10342845 and REF_RGD_ID:8694156

Molecular Function

  
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)ESR2BonoboDNA binding enablesIEAUniProtKB-KW:KW-0238150520179 UniProtGO_REF:0000043ESR2BonoboDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOEsr2 (Rattus norvegicus)9068941PMID:12047722NTNU_SBPMID:12047722 and REF_RGD_ID:8661629ESR2Bonoboenzyme binding  ISODnmt1 (Rattus norvegicus)9068941 RGDPMID:19683557 and REF_RGD_ID:8694315ESR2Bonoboenzyme binding enablesIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonoboestradiol binding  ISOestradiol9068941 RGDPMID:9292936 and REF_RGD_ID:8694325ESR2Bonoboestrogen binding  ISObeta-Zearalanol more ...9068941 RGDPMID:9048584 and REF_RGD_ID:8694130ESR2Bonoboestrogen response element binding  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:9600083 and REF_RGD_ID:728646ESR2Bonoboestrogen response element binding enablesIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonoboestrogen response element binding enablesIEAPANTHER:PTN000639432150520179 TreeGrafterGO_REF:0000118ESR2Bonoboheterocyclic compound binding  ISONafoxidine9068941 RGDPMID:9048584 and REF_RGD_ID:8694130ESR2Bonoboheterocyclic compound binding  ISOgenistein9068941 RGDPMID:9292936 and REF_RGD_ID:8694325ESR2Bonobohormone binding  ISOdiethylstilbestrol9068941 RGDPMID:9048584 and REF_RGD_ID:8694130ESR2Bonobohormone binding  ISOEsr2 (Rattus norvegicus)906894117-beta-estradiol E2RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonobohormone binding  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:15105439 and REF_RGD_ID:1580331ESR2Bonobometal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043ESR2Bonobonuclear estrogen receptor activity enablesIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonobonuclear estrogen receptor activity enablesIEAInterPro:IPR028355150520179 InterProGO_REF:0000002ESR2Bonobonuclear receptor activity enablesIEAPANTHER:PTN000639432150520179 TreeGrafterGO_REF:0000118ESR2Bonobonuclear receptor activity enablesIEAInterPro:IPR028355150520179 InterProGO_REF:0000002ESR2Bonobonuclear receptor activity enablesIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonobonuclear steroid receptor activity  ISOEsr2 (Rattus norvegicus)906894117-beta-estradiol E2RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonobonuclear steroid receptor activity enablesIEAInterPro:IPR024178150520179 InterProGO_REF:0000002ESR2Bonoboorganic cyclic compound binding  ISOafimoxifene9068941 RGDPMID:9292936 and REF_RGD_ID:8694325ESR2Bonoboorganic cyclic compound binding enablesIEAARBA:ARBA00028014150520179 UniProtGO_REF:0000117ESR2Bonoboorganic cyclic compound binding  ISOtamoxifen more ...9068941 RGDPMID:9048584 and REF_RGD_ID:8694130ESR2Bonoboperoxisome proliferator activated receptor binding  ISOPparg (Rattus norvegicus)9068941 RGDPMID:20689342 and REF_RGD_ID:8553035ESR2Bonobopromoter-specific chromatin binding  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:24046281 and REF_RGD_ID:7364871ESR2Bonoboprotein binding enablesISOPR:Q8VH519068941 PMID:11704680MGIPMID:11704680ESR2Bonoboprotein binding enablesISOUniProtKB:A6HD629068941PMID:21808025UniProtPMID:21808025 and REF_RGD_ID:13432273ESR2Bonoboprotein binding enablesISOUniProtKB:A8MQ03 more ...9068941 PMID:32296183IntActPMID:32296183ESR2Bonoboprotein binding enablesISOUniProtKB:O15162 more ...9068941 PMID:25910212IntActPMID:25910212ESR2Bonoboprotein binding enablesISOUniProtKB:P00533 and UniProtKB:P383989068941 PMID:21951318IntActPMID:21951318ESR2Bonoboprotein binding enablesISOUniProtKB:O151629068941 PMID:24722188 and PMID:25416956IntActPMID:24722188 and PMID:25416956ESR2Bonoboprotein binding enablesISOUniProtKB:Q8N1639068941 PMID:20074560UniProtPMID:20074560ESR2Bonoboprotein binding enablesISOUniProtKB:P292799068941 PMID:21629692IntActPMID:21629692ESR2Bonoboprotein binding enablesISOUniProtKB:Q609749068941 PMID:12904255IntActPMID:12904255ESR2Bonoboprotein binding enablesISOUniProtKB:Q6P9F09068941 PMID:19126643ParkinsonsUK-UCLPMID:19126643ESR2Bonoboprotein binding enablesISOUniProtKB:Q96T769068941 PMID:11279242UniProtPMID:11279242ESR2Bonoboprotein binding enablesISOUniProtKB:P530419068941 PMID:14764652IntActPMID:14764652ESR2Bonoboprotein binding enablesISOUniProtKB:O435249068941 PMID:18312651IntActPMID:18312651ESR2Bonoboprotein binding enablesISOUniProtKB:Q5VJS59068941PMID:19423554UniProtPMID:19423554 and REF_RGD_ID:8553436ESR2Bonoboprotein binding enablesISOUniProtKB:P011019068941 MGI:5013670 and PMID:21565615IntActMGI:5013670 and PMID:21565615ESR2Bonoboprotein binding  ISOPgr (Rattus norvegicus)9068941 RGDPMID:16020483 and REF_RGD_ID:7248707ESR2Bonoboprotein binding  ISONcor1 (Rattus norvegicus)9068941 RGDPMID:19460436 and REF_RGD_ID:5688174ESR2Bonoboprotein binding  ISONcoa1 (Rattus norvegicus)9068941 RGDPMID:19460436 and REF_RGD_ID:5688174ESR2Bonoboprotein binding enablesISOUniProtKB:P03372-19068941 PMID:19022902IntActPMID:19022902ESR2Bonoboprotein binding  ISONrip1 (Rattus norvegicus)9068941 RGDPMID:19460436 and REF_RGD_ID:5688174ESR2Bonoboprotein binding enablesISOUniProtKB:Q16881-49068941 PMID:15199063IntActPMID:15199063ESR2Bonoboprotein binding  ISOPcna (Rattus norvegicus)9068941 RGDPMID:19683557 and REF_RGD_ID:8694315ESR2BonoboRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAUniProtKB:Q92731 and ensembl:ENSP00000343925150520179 EnsemblGO_REF:0000107ESR2Bonobosequence-specific DNA binding  ISOEsr2 (Rattus norvegicus)9068941 RGDPMID:12200235 and REF_RGD_ID:1582280ESR2Bonobosequence-specific DNA binding enablesIEAInterPro:IPR001628150520179 InterProGO_REF:0000002ESR2Bonobosteroid binding  ISOEsr2 (Rattus norvegicus)906894117-beta-estradiol E2RGDPMID:17928626 and REF_RGD_ID:5128669ESR2Bonobosteroid binding enablesIEAInterPro:IPR024178150520179 InterProGO_REF:0000002ESR2Bonobosteroid hormone binding  ISOestriol more ...9068941 RGDPMID:9048584 and REF_RGD_ID:8694130ESR2Bonobozinc ion binding enablesIEAInterPro:IPR001628 more ...150520179 InterProGO_REF:0000002

Molecular Pathway Annotations    Click to see Annotation Detail View

RGD Manual Annotations


  
Disease Annotations     Click to see Annotation Detail View
adenocarcinoma  (ISO)
adenoma  (ISO)
alopecia  (ISO)
Alzheimer's disease  (ISO)
Animal Mammary Neoplasms  (ISO)
anxiety disorder  (ISO)
aortic valve stenosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
Blast Crisis  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
Cardiac Arrhythmias  (ISO)
Cocaine-Related Disorders  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (ISO)
colon cancer  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
contact dermatitis  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cystitis  (ISO)
Deafness  (ISO)
depressive disorder  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Melanoma  (ISO)
Female Infertility  (ISO)
glomerulosclerosis  (ISO)
Graves' disease  (ISO)
Hand Osteoarthritis  (ISO)
Hashimoto Disease  (ISO)
Hearing Loss  (ISO)
Hemorrhagic Shock  (ISO)
Hot Flashes  (ISO)
Hyperalgesia  (ISO)
hypertension  (ISO)
hypospadias  (ISO)
in situ carcinoma  (ISO)
inflammatory bowel disease  (ISO)
interstitial cystitis  (ISO)
Knee Osteoarthritis  (ISO)
Left Ventricular Hypertrophy  (ISO)
Lithiasis  (ISO)
Lung Injury  (ISO)
malignant astrocytoma  (ISO)
medulloblastoma  (ISO)
melanoma  (ISO)
myasthenia gravis  (ISO)
myeloid leukemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplastic Cell Transformation  (ISO)
obesity  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
Osteoporotic Fractures  (ISO)
ovarian dysgenesis 8  (ISO)
Parkinson's disease  (ISO)
peritonitis  (ISO)
Pituitary Neoplasms  (ISO)
Postmenopausal Osteoporosis  (ISO)
pre-eclampsia  (ISO)
primary open angle glaucoma  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (ISO)
prostatic hypertrophy  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (ISO)
retinal degeneration  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
Spinal Cord Injuries  (ISO)
Splenomegaly  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Urination Disorders  (ISO)
Varicose Ulcer  (ISO)
Vulvar Lichen Sclerosus  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amygdala development  (ISO)
androgen receptor signaling pathway  (ISO)
behavioral fear response  (ISO)
brain development  (ISO)
cell population proliferation  (ISO)
cellular response to estradiol stimulus  (IEA,ISO)
cellular response to estrogen stimulus  (IEA)
cellular response to lipopolysaccharide  (ISO)
cellular response to magnetism  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebellum development  (ISO)
epithelial cell maturation involved in prostate gland development  (ISO)
epithelial cell proliferation  (ISO)
estrogen receptor signaling pathway  (IEA,ISO)
estrous cycle  (ISO)
female gonad development  (ISO)
hormone-mediated apoptotic signaling pathway  (ISO)
hypothalamus development  (ISO)
learning or memory  (ISO)
male gonad development  (ISO)
negative regulation of androgen receptor signaling pathway  (ISO)
negative regulation of behavior  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of feeding behavior  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of reactive oxygen species metabolic process  (ISO)
negative regulation of smooth muscle cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
neuron migration  (ISO)
nuclear receptor-mediated steroid hormone signaling pathway  (ISO)
ovarian follicle development  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of epidermal growth factor receptor signaling pathway  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
prostate gland development  (ISO)
prostate gland epithelium morphogenesis  (ISO)
regulation of cell population proliferation  (ISO)
regulation of DNA-templated transcription  (IEA)
regulation of transcription by RNA polymerase II  (IEA)
response to activity  (ISO)
response to bisphenol A  (ISO)
response to dexamethasone  (ISO)
response to estradiol  (ISO)
response to estrogen  (ISO)
response to ethanol  (ISO)
response to genistein  (ISO)
response to hormone  (ISO)
response to human chorionic gonadotropin  (ISO)
response to insecticide  (ISO)
response to lipid  (IEA)
response to nutrient levels  (ISO)
response to organic cyclic compound  (IEA,ISO)
response to salt  (ISO)
response to testosterone  (ISO)
response to xenobiotic stimulus  (ISO)
Sertoli cell development  (ISO)
Sertoli cell proliferation  (ISO)
uterus development  (ISO)
vagina development  (ISO)
vasodilation  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ESR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan1-v2NHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBINHGRI_mPanPan1Mhudiblu_PPA_v01444,807,875 - 44,919,780 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3PanPan1.11463,064,397 - 63,175,303 (-)NCBIpanpan1.1PanPan1.1panPan2PanPan1.1 Ensembl1463,064,402 - 63,131,303 (-)Ensemblpanpan1.1panPan2
ESR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,226,707 - 64,338,613 (-)NCBIGRCh38GRCh38hg38GRCh38GRCh38.p14 Ensembl1464,084,232 - 64,338,112 (-)EnsemblGRCh38hg38GRCh38GRCh371464,693,425 - 64,805,331 (-)NCBIGRCh37GRCh37hg19GRCh37Build 361463,763,504 - 63,875,021 (-)NCBINCBI36Build 36hg18NCBI36Build 341463,769,607 - 63,830,831NCBICelera1444,751,460 - 44,862,976 (-)NCBICeleraCytogenetic Map14q23.2-q23.3NCBIHuRef1444,866,333 - 44,977,880 (-)NCBIHuRefCHM1_11464,633,573 - 64,745,077 (-)NCBICHM1_1T2T-CHM13v2.01458,434,422 - 58,546,317 (-)NCBIT2T-CHM13v2.0
Esr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391276,167,193 - 76,224,033 (-)NCBIGRCm39GRCm39mm39GRCm39 Ensembl1276,167,193 - 76,224,033 (-)EnsemblGRCm39 EnsemblGRCm381276,120,419 - 76,177,259 (-)NCBIGRCm38GRCm38mm10GRCm38GRCm38.p6 Ensembl1276,120,419 - 76,177,259 (-)EnsemblGRCm38mm10GRCm38MGSCv371277,221,406 - 77,278,246 (-)NCBIGRCm37MGSCv37mm9NCBIm37MGSCv361277,039,259 - 77,096,099 (-)NCBIMGSCv36mm8Celera1277,215,189 - 77,271,340 (-)NCBICeleraCytogenetic Map12C3NCBIcM Map1233.52NCBI
Esr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86100,589,553 - 100,645,240 (-)NCBIGRCr8mRatBN7.2694,858,438 - 94,909,630 (-)NCBImRatBN7.2mRatBN7.2mRatBN7.2 Ensembl694,809,547 - 94,908,919 (-)EnsemblmRatBN7.2 EnsemblUTH_Rnor_SHR_Utx695,252,364 - 95,302,093 (-)NCBIRnor_SHRUTH_Rnor_SHR_UtxUTH_Rnor_SHRSP_BbbUtx_1.0695,550,861 - 95,600,589 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_WKY_Bbb_1.0694,979,673 - 95,029,407 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0Rnor_6.0699,163,953 - 99,214,711 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0Rnor_6.0 Ensembl699,164,357 - 99,214,251 (-)EnsemblRnor6.0rn6Rnor6.0Rnor_5.06108,576,398 - 108,626,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0RGSC_v3.4698,691,167 - 98,775,299 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4RGSC_v3.1698,694,622 - 98,778,755 (-)NCBICelera693,284,596 - 93,334,744 (-)NCBICeleraRH 3.4 Map6686.1RGDCytogenetic Map6q24NCBI
Esr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554665,575,088 - 5,638,946 (+)EnsemblChiLan1.0ChiLan1.0NW_0049554665,587,003 - 5,644,765 (+)NCBIChiLan1.0ChiLan1.0
ESR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1838,645,917 - 38,715,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1CanFam3.1 Ensembl838,645,430 - 38,702,691 (-)EnsemblCanFam3.1canFam3CanFam3.1Dog10K_Boxer_Tasha838,338,303 - 38,407,225 (-)NCBIDog10K_Boxer_TashaROS_Cfam_1.0838,869,013 - 38,937,387 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0 Ensembl838,868,526 - 38,925,228 (-)EnsemblROS_Cfam_1.0 EnsemblUMICH_Zoey_3.1838,489,186 - 38,557,866 (-)NCBIUMICH_Zoey_3.1UNSW_CanFamBas_1.0838,561,325 - 38,629,870 (-)NCBIUNSW_CanFamBas_1.0UU_Cfam_GSD_1.0838,921,461 - 38,990,144 (-)NCBIUU_Cfam_GSD_1.0
Esr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864066,173,041 - 66,235,531 (+)NCBIHiC_Itri_2SpeTri2.0 EnsemblNW_0049364957,956,766 - 8,004,357 (-)EnsemblSpeTri2.0SpeTri2.0 EnsemblSpeTri2.0NW_0049364957,956,168 - 8,018,356 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1193,829,560 - 193,906,565 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1Sscrofa11.11193,823,666 - 193,907,330 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1Sscrofa10.21215,715,909 - 215,788,512 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12441,426,333 - 41,513,802 (-)NCBIChlSab1.1ChlSab1.1chlSab2ChlSab1.1 Ensembl2441,447,224 - 41,512,486 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2Vero_WHO_p1.0NW_02366605329,619,854 - 29,688,619 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Esr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473436,759,104 - 36,825,295 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2HetGla 1.0NW_00462473436,742,913 - 36,862,993 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008956961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014347559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063596237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063596238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide EU213025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JARIFH020000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000040596   ⟹   ENSPPAP00000017876
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1463,064,402 - 63,131,303 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040603   ⟹   ENSPPAP00000017883
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1463,065,529 - 63,120,350 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040608   ⟹   ENSPPAP00000017887
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1463,069,334 - 63,120,260 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040612   ⟹   ENSPPAP00000017891
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1463,070,720 - 63,131,303 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040616   ⟹   ENSPPAP00000017895
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1463,070,720 - 63,120,350 (-)Ensembl
RefSeq Acc Id: XM_055097687   ⟹   XP_054953662
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan11464,559,370 - 64,666,706 (-)NCBI
RefSeq Acc Id: XM_055097689   ⟹   XP_054953664
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBI
RefSeq Acc Id: XM_055097690   ⟹   XP_054953665
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBI
RefSeq Acc Id: XM_055097691   ⟹   XP_054953666
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBI
RefSeq Acc Id: XM_055097692   ⟹   XP_054953667
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBI
RefSeq Acc Id: XM_057299721   ⟹   XP_057155704
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,405,940 (-)NCBINHGRI_mPanPan11464,559,211 - 64,622,455 (-)NCBI
RefSeq Acc Id: XM_057299722   ⟹   XP_057155705
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBINHGRI_mPanPan11464,555,234 - 64,666,706 (-)NCBI
RefSeq Acc Id: XM_057299723   ⟹   XP_057155706
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,405,979 (-)NCBINHGRI_mPanPan11464,555,234 - 64,622,494 (-)NCBI
RefSeq Acc Id: XM_057299724   ⟹   XP_057155707
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,405,697 (-)NCBINHGRI_mPanPan11464,555,234 - 64,622,212 (-)NCBI
RefSeq Acc Id: XM_063596237   ⟹   XP_063452307
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBI
RefSeq Acc Id: XM_063596238   ⟹   XP_063452308
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21565,338,719 - 65,450,191 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054953662 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953664 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953665 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953666 (Get FASTA)   NCBI Sequence Viewer  
  XP_054953667 (Get FASTA)   NCBI Sequence Viewer  
  XP_057155704 (Get FASTA)   NCBI Sequence Viewer  
  XP_057155705 (Get FASTA)   NCBI Sequence Viewer  
  XP_057155706 (Get FASTA)   NCBI Sequence Viewer  
  XP_057155707 (Get FASTA)   NCBI Sequence Viewer  
  XP_063452307 (Get FASTA)   NCBI Sequence Viewer  
  XP_063452308 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABY64727 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000017876.1
  ENSPPAP00000017883.1
  ENSPPAP00000017887.1
  ENSPPAP00000017891.1
  ENSPPAP00000017895.1
RefSeq Acc Id: ENSPPAP00000017876   ⟸   ENSPPAT00000040596
RefSeq Acc Id: ENSPPAP00000017883   ⟸   ENSPPAT00000040603
RefSeq Acc Id: ENSPPAP00000017887   ⟸   ENSPPAT00000040608
RefSeq Acc Id: ENSPPAP00000017891   ⟸   ENSPPAT00000040612
RefSeq Acc Id: ENSPPAP00000017895   ⟸   ENSPPAT00000040616
RefSeq Acc Id: XP_054953665   ⟸   XM_055097690
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AL89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953667   ⟸   XM_055097692
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AL89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953664   ⟸   XM_055097689
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AKI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953666   ⟸   XM_055097691
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AL89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054953662   ⟸   XM_055097687
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AKJ3 (UniProtKB/TrEMBL),   B6CK26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155705   ⟸   XM_057299722
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AKI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155706   ⟸   XM_057299723
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AKI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155707   ⟸   XM_057299724
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AL89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155704   ⟸   XM_057299721
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AKJ3 (UniProtKB/TrEMBL),   B6CK26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063452307   ⟸   XM_063596237
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AKJ3 (UniProtKB/TrEMBL),   B6CK26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063452308   ⟸   XM_063596238
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AKJ3 (UniProtKB/TrEMBL),   B6CK26 (UniProtKB/TrEMBL)
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040596.1 UniProtKB/TrEMBL
  ENSPPAT00000040603.1 UniProtKB/TrEMBL
  ENSPPAT00000040608.1 UniProtKB/TrEMBL
  ENSPPAT00000040612.1 UniProtKB/TrEMBL
  ENSPPAT00000040616.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/TrEMBL
InterPro ER-beta/gamma UniProtKB/TrEMBL
  Est_rcpt/est-rel_rcp UniProtKB/TrEMBL
  Estrogen_rcpt_beta_N UniProtKB/TrEMBL
  NHR-like_dom_sf UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
KEGG Report pps:100988122 UniProtKB/TrEMBL
NCBI Gene ESR2 ENTREZGENE
PANTHER ESTROGEN RECEPTOR BETA UniProtKB/TrEMBL
  KNIRPS-RELATED PROTEIN-RELATED UniProtKB/TrEMBL
Pfam ERbeta_N UniProtKB/TrEMBL
  Hormone_recep UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PIRSF ER-b UniProtKB/TrEMBL
  ER-like_NR UniProtKB/TrEMBL
PRINTS STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF48508 UniProtKB/TrEMBL
UniProt A0A2R9AKI0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AKI6_PANPA UniProtKB/TrEMBL
  A0A2R9AKJ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AL89 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AQ73_PANPA UniProtKB/TrEMBL
  B6CK26 ENTREZGENE, UniProtKB/TrEMBL

 


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