doi: 10.1111/j.1742-1241.2005.00500.x.
The mean platelet volume in patients with obesity
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- PMID: 16033624
- DOI: 10.1111/j.1742-1241.2005.00500.x
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The mean platelet volume in patients with obesity
Int J Clin Pract.
2005 Aug.
Abstract
Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate MPV in patients with obesity compared with non-obese control subjects. We selected 100 non-obese subjects and 100 subjects with obesity [body mass index (BMI) > or =30 kg/m(2)] matched for age and gender. The MPV was significantly higher in obese group than in non-obese control group (10.3 +/- 1.2 vs. 9.0 +/- 0.8 fl, p < 0.01). MPV was positively correlated with BMI in obese group (p < 0.05). Increased MPV may be a possible cause for increased cardiovascular risk in patients with obesity.
Comment in
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Mean platelet volume is not correlated with body mass index in patients with microcytic anaemia.Int J Clin Pract. 2006 Jul;60(7):871-2; author reply 870-1. doi: 10.1111/j.1368-5031.2006.0919c.x. Int J Clin Pract. 2006. PMID: 16862638 No abstract available.
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