[Obesity and oxidative stress: role of antioxidant supplementation]
- PMID: 19637727
[Obesity and oxidative stress: role of antioxidant supplementation]
Abstract
The prevalence of obesity has significantly increased during the last decades reaching epidemic proportions in many countries. Obesity has been described as a state of chronic oxidative stress. Furthermore, oxidative stress has been defined as the link between obesity and its major associated disorders such as insulin resistance, hypertension, etc. Because of this, recent studies have suggested the potential therapeutic role of dietary antioxidant supplementation in the reduction of body weight or its beneficial effect on several obesity related disorders. This review updates the data described during the last years (2002-2008) regarding the relationship between obesity and oxidative stress as well as the role of dietary antioxidant supplementation in the reduction of oxidative stress, obesity and its principal associated comorbidities. Despite the available data, here summarized, further studies are needed in order to deeply understand the molecular mechanisms involved in the beneficial effects of dietary antioxidants on obesity and associated disorders.
Similar articles
-
Dietary antioxidants and glucose metabolism.Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):471-6. doi: 10.1097/MCO.0b013e328303be79. Curr Opin Clin Nutr Metab Care. 2008. PMID: 18542009 Review.
-
Oxidative stress and role of antioxidant supplementation in critical illness.Clin Lab. 2007;53(3-4):199-209. Clin Lab. 2007. PMID: 17447658 Review.
-
[The role of antioxidants in prevention].Orv Hetil. 2006 Apr 2;147(13):603-7. Orv Hetil. 2006. PMID: 16623442 Review. Hungarian.
-
Can oxidative damage be treated nutritionally?Clin Nutr. 2005 Apr;24(2):172-83. doi: 10.1016/j.clnu.2004.10.003. Clin Nutr. 2005. PMID: 15784476 Review.
-
Effects of antioxidants on immune system ageing.Eur J Clin Nutr. 2002 Aug;56 Suppl 3:S5-8. doi: 10.1038/sj.ejcn.1601476. Eur J Clin Nutr. 2002. PMID: 12142953 Review.
Cited by
-
Role of Goldenberry (Fruits with Husk) Extract in Ameliorating the Architecture and Osmotic Fragility of Red Blood Cells in Obese Rats.Biomed Res Int. 2023 Nov 27;2023:8794214. doi: 10.1155/2023/8794214. eCollection 2023. Biomed Res Int. 2023. PMID: 38054046 Free PMC article.
-
Chromatographic Analyses of Spirulina (Arthrospira platensis) and Mechanism of Its Protective Effects against Experimental Obesity and Hepatic Steatosis in Rats.Medicina (Kaunas). 2023 Oct 13;59(10):1823. doi: 10.3390/medicina59101823. Medicina (Kaunas). 2023. PMID: 37893541 Free PMC article.
-
Extraction, Isolation of Bioactive Compounds and Therapeutic Potential of Rapeseed (Brassica napus L.).Molecules. 2022 Dec 12;27(24):8824. doi: 10.3390/molecules27248824. Molecules. 2022. PMID: 36557956 Free PMC article. Review.
-
Protective Effects of Bisoprolol Against Cadmium-induced Myocardial Toxicity Through Inhibition of Oxidative Stress and NF-κΒ Signalling in Rats.J Vet Res. 2021 Oct 20;65(4):505-511. doi: 10.2478/jvetres-2021-0054. eCollection 2021 Dec. J Vet Res. 2021. PMID: 35112006 Free PMC article.
-
Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial.Clin Nutr Res. 2019 Oct 28;8(4):318-328. doi: 10.7762/cnr.2019.8.4.318. eCollection 2019 Oct. Clin Nutr Res. 2019. PMID: 31720257 Free PMC article.