Local frequency dependence in transcranial ultrasound transmission
The development of large-aperture multiple-source transducer arrays for ultrasound
transmission through the human skull has demonstrated the possibility of controlled and …
transmission through the human skull has demonstrated the possibility of controlled and …
Demonstration of potential noninvasive ultrasound brain therapy through an intact skull
Utilization of therapeutic ultrasound in the brain has been seriously limited by the commonly
accepted view that these exposures would require that a piece of the skull bone be removed …
accepted view that these exposures would require that a piece of the skull bone be removed …
Characterization of ultrasound propagation through ex-vivo human temporal bone
AY Ammi, TD Mast, IH Huang, TA Abruzzo… - Ultrasound in medicine …, 2008 - Elsevier
Adjuvant therapies that lower the thrombolytic dose or increase its efficacy would represent
a significant breakthrough in the treatment of patients with ischemic stroke. The objective of …
a significant breakthrough in the treatment of patients with ischemic stroke. The objective of …
Design of patient-specific focused ultrasound arrays for non-invasive brain therapy with increased trans-skull transmission and steering range
A Hughes, K Hynynen - Physics in Medicine & Biology, 2017 - iopscience.iop.org
The use of a phased array of ultrasound transducer elements to sonicate through the skull
has opened the way for new treatments and the delivery of therapeutics beyond the blood …
has opened the way for new treatments and the delivery of therapeutics beyond the blood …
The role of internal reflection in transskull phase distortion
GT Clement, J Sun, K Hynynen - Ultrasonics, 2001 - Elsevier
Phase distortion due to reflection in transcranial ultrasound propagation is investigated.
Understanding of these phase-dependent properties is motivated by efforts to construct a …
Understanding of these phase-dependent properties is motivated by efforts to construct a …
Observation of guided acoustic waves in a human skull
Human skull poses a significant barrier for the propagation of ultrasound waves.
Development of methods enabling more efficient ultrasound transmission into and from the …
Development of methods enabling more efficient ultrasound transmission into and from the …
Investigation of a large-area phased array for focused ultrasound surgery through the skull
GT Clement, J White, K Hynynen - Physics in Medicine & Biology, 2000 - iopscience.iop.org
Non-invasive treatment of brain disorders using ultrasound would require a transducer array
that can propagate ultrasound through the skull and still produce sufficient acoustic pressure …
that can propagate ultrasound through the skull and still produce sufficient acoustic pressure …
A Magnetic Resonance Imaging–Compatible, Large‐Scale Array for Trans‐Skull Ultrasound Surgery and Therapy
Objective Advances in ultrasound transducer array and amplifier technologies have
prompted many intriguing scientific proposals for ultrasound therapy. These include both …
prompted many intriguing scientific proposals for ultrasound therapy. These include both …
Adaptive focusing for transcranial ultrasound imaging using dual arrays
Ultrasonic brain imaging remains difficult and limited because of the strong aberrating
effects of the skull (absorption, diffusion and refraction of ultrasounds): high resolution …
effects of the skull (absorption, diffusion and refraction of ultrasounds): high resolution …
Acoustic properties across the human skull
Transcranial ultrasound is emerging as a noninvasive tool for targeted treatments of brain
disorders. Transcranial ultrasound has been used for remotely mediated surgeries, transient …
disorders. Transcranial ultrasound has been used for remotely mediated surgeries, transient …