Possible interactions between antioxidant enzymes and free sialic acids in saliva: a preliminary study on elite judoists
- PMID: 16320166
- DOI: 10.1055/s-2005-837465
Possible interactions between antioxidant enzymes and free sialic acids in saliva: a preliminary study on elite judoists
Abstract
Measurement of antioxidant enzyme activities is of great importance in the evaluation of oxidative stress in human metabolism. Sialic acids are also vital bio-markers for some diseases such as acute myocardial infarction and diabetes. In the present study, antioxidant enzyme activities (SOD, CAT, GSH-Px) and free sialic acid (FSA) levels in saliva were determined before and after training in the elite Turkish judoists (ETJ). According to the results, antioxidant enzyme activities in post-exercise values were significantly (p < 0.05) higher than those of pre-exercise values. A major finding of this study was that FSA levels also increased significantly (p < 0.05). Superoxide radical anion might have been effectively dismutated to hydrogen peroxide by elevated SOD activity. Accordingly, it suggests that CAT, having a higher increasing rate, was more efficient than GSH-Px in decomposition of hydrogen peroxide. In conclusion, the increase in antioxidant enzyme activities might have caused the elevation of FSA levels after training. Over-excreted sialic acids to saliva might have an important role in the removal of hydrogen peroxide. Since the increase in FSA levels in saliva has been found to be in well accordance with antioxidant enzymes, FSA may be concluded as an alternative oxidative stress marker in athletes.
Similar articles
-
No indications of persistent oxidative stress in response to an ironman triathlon.Med Sci Sports Exerc. 2008 Dec;40(12):2119-28. doi: 10.1249/MSS.0b013e3181824dab. Med Sci Sports Exerc. 2008. PMID: 18981936
-
Investigation of free radical scavenging enzyme activities and lipid peroxidation in human placental tissues with miscarriage.J Soc Gynecol Investig. 2006 Jul;13(5):384-8. doi: 10.1016/j.jsgi.2006.04.003. J Soc Gynecol Investig. 2006. PMID: 16814167
-
Comparison of antioxidant enzymes in saliva of elderly smokers and non-smokers.Gerodontology. 2006 Mar;23(1):38-42. doi: 10.1111/j.1741-2358.2006.00077.x. Gerodontology. 2006. PMID: 16433640
-
[Antioxidant role of saliva in maintaining oral health].Vojnosanit Pregl. 2005 Jul-Aug;62(7-8):575-9. doi: 10.2298/vsp0508575t. Vojnosanit Pregl. 2005. PMID: 16171022 Review. Serbian. No abstract available.
-
The levels of plasma and salivary antioxidants in the patient with recurrent aphthous stomatitis.J Oral Pathol Med. 2005 Jan;34(1):7-12. doi: 10.1111/j.1600-0714.2004.00253.x. J Oral Pathol Med. 2005. PMID: 15610400
Cited by
-
The Relationship between Exercise and Salivary Oxidative Stress: A Systematic Review.Antioxidants (Basel). 2022 Jul 29;11(8):1489. doi: 10.3390/antiox11081489. Antioxidants (Basel). 2022. PMID: 36009209 Free PMC article. Review.
-
Influence of Swimming Training Session on Selected Saliva Components in Youth Swimmers.Front Physiol. 2022 Apr 14;13:869903. doi: 10.3389/fphys.2022.869903. eCollection 2022. Front Physiol. 2022. PMID: 35492619 Free PMC article.
-
The Effect of Acute Intense Exercise on Activity of Antioxidant Enzymes in Smokers and Non-Smokers.Biomolecules. 2021 Jan 27;11(2):171. doi: 10.3390/biom11020171. Biomolecules. 2021. PMID: 33513978 Free PMC article.
-
The effects of isoflavone supplementation plus combined exercise on salivary markers of oxidative stress in postmenopausal women.J Clin Biochem Nutr. 2020 Jan;66(1):43-48. doi: 10.3164/jcbn.19-44. Epub 2019 Oct 31. J Clin Biochem Nutr. 2020. PMID: 32001955 Free PMC article.
-
Salivary and Plasmatic Antioxidant Profile following Continuous, Resistance, and High-Intensity Interval Exercise: Preliminary Study.Oxid Med Cell Longev. 2019 Nov 26;2019:5425021. doi: 10.1155/2019/5425021. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31885802 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous