Trans-skull ultrasound therapy: The feasibility of using image-derived skull thickness information to correct the phase distortion
K Hynynen, J Sun - IEEE transactions on ultrasonics …, 1999 - ieeexplore.ieee.org
Recent papers have shown that focused ultrasound therapy may be feasible in the brain
through an intact human skull by using phased arrays to correct the phase distortion induced …
through an intact human skull by using phased arrays to correct the phase distortion induced …
Correlation of ultrasound phase with physical skull properties
GT Clement, K Hynynen - Ultrasound in medicine & biology, 2002 - Elsevier
Noninvasive treatment of brain disorders using focused ultrasound (US) requires a reliable
model for predicting the distortion of the field due to the skull using physical parameters …
model for predicting the distortion of the field due to the skull using physical parameters …
Demonstration of potential noninvasive ultrasound brain therapy through an intact skull
Utilization of therapeutic ultrasound in the brain has been seriously limited by the commonly
accepted view that these exposures would require that a piece of the skull bone be removed …
accepted view that these exposures would require that a piece of the skull bone be removed …
A Magnetic Resonance Imaging–Compatible, Large‐Scale Array for Trans‐Skull Ultrasound Surgery and Therapy
Objective Advances in ultrasound transducer array and amplifier technologies have
prompted many intriguing scientific proposals for ultrasound therapy. These include both …
prompted many intriguing scientific proposals for ultrasound therapy. These include both …
Focusing of therapeutic ultrasound through a human skull: a numerical study
J Sun, K Hynynen - The Journal of the Acoustical Society of America, 1998 - pubs.aip.org
A numerical model was developed which can use digitized layer interfaces to calculate
ultrasound wave absorption, diffraction, reflection, and refraction. This model was used to …
ultrasound wave absorption, diffraction, reflection, and refraction. This model was used to …
A non-invasive method for focusing ultrasound through the human skull
GT Clement, K Hynynen - Physics in medicine & biology, 2002 - iopscience.iop.org
A technique for focusing ultrasound through the human skull is described and verified. The
approach is based on a layered wavevector-frequency domain model, which propagates …
approach is based on a layered wavevector-frequency domain model, which propagates …
A hemisphere array for non-invasive ultrasound brain therapy and surgery
GT Clement, J Sun, T Giesecke… - Physics in Medicine & …, 2000 - iopscience.iop.org
Ultrasound phased arrays may offer a method for non-invasive deep brain surgery through
the skull. In this study a hemispherical phased array system is developed to test the …
the skull. In this study a hemispherical phased array system is developed to test the …
Investigation of a large-area phased array for focused ultrasound surgery through the skull
GT Clement, J White, K Hynynen - Physics in Medicine & Biology, 2000 - iopscience.iop.org
Non-invasive treatment of brain disorders using ultrasound would require a transducer array
that can propagate ultrasound through the skull and still produce sufficient acoustic pressure …
that can propagate ultrasound through the skull and still produce sufficient acoustic pressure …
Transcranial ultrasound focus reconstruction with phase and amplitude correction
J White, GT Clement, K Hynynen - ieee transactions on …, 2005 - ieeexplore.ieee.org
Therapeutic and diagnostic ultrasound procedures performed noninvasively through the
skull require a reliable method for maintaining acoustic focus integrity after transmission …
skull require a reliable method for maintaining acoustic focus integrity after transmission …
A new ultrasound method for determining the acoustic phase shifts caused by the skull bone
J Aarnio, GT Clement, K Hynynen - Ultrasound in medicine & biology, 2005 - Elsevier
A potential noninvasive means for obtaining the value of ultrasound (US) phase shifts
caused by the skull is examined. Knowledge of these shifts could be used in new methods …
caused by the skull is examined. Knowledge of these shifts could be used in new methods …